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PROSITE entry PS00729


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PURL: https://purl.expasy.org/prosite/signature/PS00729

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General information about the entry

Entry name [info] AP_NUCLEASE_F2_1
Accession [info] PS00729
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-DEC-2001 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00599

Name and characterization of the entry

Description [info] AP endonucleases family 2 signature 1.
Pattern [info] 
H-[GSAD]-x-Y-[LIF]-[LIMN]-N-[LIVMFCAP]-[AGC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 238 in 238 different sequences
Number of true positive hits 233 in 233 different sequences
Number of 'unknown' hits 0
Number of false positive hits 5 in 5 different sequences
Number of false negative sequences 44
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 97.90 %
Recall (true positives / (true positives + false negatives)) 84.12 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] zinc at position 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 233 sequences 

APN1_CAEEL  (Q10002), APN1_PLABA  (A0A509ASK2), APN1_PLAF7  (Q8IE02),
» more

UniProtKB/Swiss-Prot
False negative sequences		 44 sequences 

APE_ASFB7   (Q65202), APE_ASFK5   (P0C9C8), APE_ASFM2   (Q65246),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

END4_THENE  (O86954), END4_YEREN  (P42691)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			5 sequences
			


			
EZH1_BOVIN  (A7E2Z2), EZH1_HUMAN  (Q92800), EZH1_MOUSE  (P70351), 

			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			14 PDB
			


			1QTW; 1QUM; 1XP3; 2NQH; 2NQJ; 2X7V; 2X7W; 3AAL; 4HNO; 5ZHZ; 8AXY; 8EDD; 
			
			

			» more