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PROSITE entry PS00721


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PURL: https://purl.expasy.org/prosite/signature/PS00721

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General information about the entry

Entry name [info] FTHFS_1
Accession [info] PS00721
Entry type [info] PATTERN
Date [info] 01-DEC-1992 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00595

Name and characterization of the entry

Description [info] Formate--tetrahydrofolate ligase signature 1.
Pattern [info] 
[GN]-[LIVMS]-K-G-[GST]-[AG]-[AST]-G-[GAS]-G-[YLHRKF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 297 in 297 different sequences
Number of true positive hits 297 in 297 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 16
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 94.89 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 297 sequences 

C1TC_DROME  (O96553), C1TC_HUMAN  (P11586), C1TC_MOUSE  (Q922D8),
» more

UniProtKB/Swiss-Prot
False negative sequences		 16 sequences 

FTHS_ACHLI  (A9NE95), FTHS_ACICJ  (A5G276), FTHS_BEII9  (B2IC30),
» more

PDB
[Detailed view]		 14 PDB

1EG7; 1FP7; 1FPM; 3DO6; 3QUS; 4IOJ; 4IOK; 4IOL; 4IOM; 4JIM; 4JJK; 4JJZ;
» more