PROSITE entry PS00720
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PURL: https://purl.expasy.org/prosite/signature/PS00720
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General information about the entry
| Entry name [info] | RASGEF |
| Accession [info] | PS00720 |
| Entry type [info] | PATTERN |
| Date [info] |
01-DEC-1992 CREATED;
01-APR-2003 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00594 |
Name and characterization of the entry
| Description [info] | Ras Guanine-nucleotide exchange factors domain signature. |
| Pattern [info] |
[VI]-P-[FYWVI]-x-[GPSV]-x(2)-[LIVMFYK]-x-[DNE]-[LIVM]-x(13,35)-[IVL]-N- [FYME]-x-K. |
Numerical results [info]
| Total number of hits | 67 in 67 different sequences |
| Number of true positive hits | 67 in 67 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 68 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 49.63 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
67 sequences
BUD5_YEAST (P25300), C3G_DROME (O77086), CDC25_CANAL (P43069),» more
|
| UniProtKB/Swiss-Prot False negative sequences |
68 sequences
BCAR3_BOVIN (Q58DL5), BCAR3_HUMAN (O75815), BCAR3_MACFA (Q4R8R1),» more |
| PDB [Detailed view] |
107 PDB
1BKD; 1NVU; 1NVV; 1NVW; 1NVX; 1XD2; 1XD4; 1XDV; 2BYV; 2II0; 2IJE; 3CF6; » more |