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Entry: PS00697

General information about the entry
Entry nameDNA_LIGASE_A1
Accession numberPS00697
Entry typePATTERN
DateDEC-1992 (CREATED); APR-2006 (DATA UPDATE); NOV-2008 (INFO UPDATE).
PROSITE DocumentationPDOC00295
Associated ProRulePRU10135
Name and characterization of the entry
DescriptionATP-dependent DNA ligase AMP-binding site.
Pattern[EDQH]-{K}-K-{VEDI}-[DN]-G-{GLYN}-R-[GACIVM].
Numerical results
  • UniProtKB/Swiss-Prot release number: 56.6, total number of sequence entries in that release: 405506.
  • Total number of hits in UniProtKB/Swiss-Prot: 111 hits in 106 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 79 hits in 79 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 32 hits in 27 different sequences
  • Number of known missed hits: 6
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 71.17 %
  • Recall (true hits / (true hits + false negatives)): 92.94 %
Comments
  • Taxonomic range: Archaebacteria, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
  • Maximum known number of repetitions of the pattern in a single protein: 4
  • `Interesting' site in the pattern: 3,active_site(?)
  • VERSION: 2
Cross-references
UniProtKB/Swiss-ProtTrue positive hits:
DNLI1_ARATH (Q42572), DNLI1_CAEEL (Q27474), DNLI1_DICDI (Q869E1), 
DNLI1_HUMAN (P18858), DNLI1_MOUSE (P37913), DNLI1_SCHPO (P12000), 
DNLI1_XENLA (P51892), DNLI1_YEAST (P04819), DNLI3_DICDI (Q54QM4), 
DNLI3_HUMAN (P49916), DNLI3_MOUSE (P97386), DNLI4_ARATH (Q9LL84), 
DNLI4_ASHGO (Q75CA4), DNLI4_ASPFU (Q4WVG8), DNLI4_ASPOR (Q2U6A1), 
DNLI4_CANAL (P52496), DNLI4_CANGA (Q6FVD8), DNLI4_CHICK (Q90YB1), 
DNLI4_COCIM (Q1DKE7), DNLI4_COPC7 (A8N936), DNLI4_COPCI (Q7Z7W5), 
DNLI4_CRYNE (Q5K9S5), DNLI4_EMENI (Q5BH83), DNLI4_HUMAN (P49917), 
DNLI4_MOUSE (Q8BTF7), DNLI4_NEUCR (Q7SB49), DNLI4_ORYSJ (Q7X7E9), 
DNLI4_PHANO (Q0UCI9), DNLI4_PONAB (Q5R6L3), DNLI4_SCHPO (O74833), 
DNLI4_YEAST (Q08387), DNLI_ACIAM  (Q02093), DNLI_AERPE  (Q9YD18), 
DNLI_AQUAE  (O67398), DNLI_ARCFU  (O29632), DNLI_ASFB7  (P35970), 
DNLI_ASFM2  (P26813), DNLI_BPT3   (P07717), DNLI_BPT4   (P00970), 
DNLI_BPT6   (P19088), DNLI_BPT7   (P00969), DNLI_FOWPV  (Q67480), 
DNLI_HALMA  (Q5V4R0), DNLI_HALSA  (Q9HR35), DNLI_IGNH4  (A8AB20), 
DNLI_METAC  (Q8TMT1), DNLI_METBF  (Q46BA3), DNLI_METBU  (Q12X08), 
DNLI_METJA  (Q57635), DNLI_METKA  (Q8TWN3), DNLI_METM5  (A4FY19), 
DNLI_METM7  (A6VFQ9), DNLI_METMA  (Q8PTK1), DNLI_METMP  (Q6LYM1), 
DNLI_METS5  (A4YD25), DNLI_METTF  (P54875), DNLI_METTH  (Q50566), 
DNLI_METTP  (A0B7F9), DNLI_NATPD  (Q3IPX0), DNLI_NPVLD  (Q9YMV2), 
DNLI_PYRAB  (Q9V185), DNLI_PYRAE  (O93723), DNLI_PYRAR  (A4WH24), 
DNLI_PYRCJ  (A3MS62), DNLI_PYRFU  (P56709), DNLI_PYRHO  (O59288), 
DNLI_PYRIL  (A1RTK4), DNLI_PYRKO  (Q9HHC4), DNLI_STRCO  (Q9FCB1), 
DNLI_SULAC  (Q4JAM1), DNLI_SULSH  (Q9P9K9), DNLI_SULSO  (Q980T8), 
DNLI_SULTO  (Q976G4), DNLI_THEFM  (Q9HH07), DNLI_VACCA  (O57250), 
DNLI_VACCC  (P20492), DNLI_VACCV  (P16272), DNLI_VARV   (P33798), 
Y1287_AQUAE (O67319)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
DNLI1_RAT   (Q9JHY8), DNLI_HAEIN  (P44121), DNLI_METS3  (A5UKX2), 
DNLI_PICTO  (Q6L195), DNLI_THEAC  (Q9HJ26), DNLI_THEVO  (Q979A1)
False positive hits (sequences which do not belong to the set under consideration):
ACVS_NOCLA  (P27743), ACVS_STRCL  (Q01757), AUBA_PYRKO  (Q5JHN3), 
AUBA_SULAC  (Q4J9H1), BDP1_HUMAN  (A6H8Y1), BDP1_MOUSE  (Q571C7), 
CITS_BACSU  (O34427), COX20_YEAST (Q04935), DDHA_RHOSU  (Q8GPG4), 
DHOM_LACLA  (Q9CGD8), DHOM_LACLC  (P52985), DLTA_LACLA  (Q9CG49), 
DSBC_BORBR  (Q7WEL4), DSBC_BORPA  (Q7W396), DSBC_BORPE  (Q7VU58), 
ERF99_ARATH (Q8L9K1), FABH_PROMM  (Q7V4F6), FOLD_BUCAI  (P57557), 
HAGA1_PORGI (P59915), HAGA2_PORGI (Q51845), INO80_USTMA (Q4PGL2), 
KUP_ANADF   (A7H902), MNME_SULNB  (A6QAL0), PAL2_SOLTU  (P31426), 
PDXB_PORGI  (Q7MV70), QUEA_DEHE1  (Q3Z8C1), RIMM_SYNR3  (A5GQ79)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]
1A0I; 1X9N; 2CFM; 2HIV; 2HIX;

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View entry in raw text format (no links)
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