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PROSITE entry PS00687


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PURL: https://purl.expasy.org/prosite/signature/PS00687

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General information about the entry

Entry name [info] ALDEHYDE_DEHYDR_GLU
Accession [info] PS00687
Entry type [info] PATTERN
Date [info] 01-JUN-1992 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00068
Associated ProRule [info] PRU10007

Name and characterization of the entry

Description [info] Aldehyde dehydrogenases glutamic acid active site.
Pattern [info] 
[LIVMFGA]-E-[LIMSTAC]-[GS]-G-[KNLM]-[SADN]-[TAPFV].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 813 in 813 different sequences
Number of true positive hits 603 in 603 different sequences
Number of 'unknown' hits 0
Number of false positive hits 210 in 210 different sequences
Number of false negative sequences 108
Number of 'partial' sequences 7
Precision (true positives / (true positives + false positives)) 74.17 %
Recall (true positives / (true positives + false negatives)) 84.81 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 2
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 603 sequences 

A9A1A_DANRE (Q7ZVB2), A9A1B_DANRE (Q802W2), AADH1_MALDO (A0A0E3T552),
» more

UniProtKB/Swiss-Prot
False negative sequences		 108 sequences 

A16A1_BOVIN (A6QR56), A16A1_HUMAN (Q8IZ83), A16A1_MOUSE (Q571I9),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 7 sequences 

AL3A1_BOVIN (P30907), AL7A1_ACASC (P83402), AL7A1_CTEID (P84463),
» more

UniProtKB/Swiss-Prot
False positive sequences		 210 sequences 

ACRB_ASPFC  (B0Y4N5), ACRB_ASPFU  (Q4WQG9), ACRB_ASPOR  (Q2UUI0),
» more

PDB
[Detailed view]		 196 PDB

1A4S; 1A4Z; 1AD3; 1AG8; 1BI9; 1BPW; 1BXS; 1CW3; 1NZW; 1NZX; 1NZZ; 1O00;
» more