PROSITE entry PS00678

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PURL: https://purl.expasy.org/prosite/signature/PS00678

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General information about the entry

Entry name [info]	WD_REPEATS_1
Accession [info]	PS00678
Entry type [info]	PATTERN
Date [info]	01-JUN-1992 CREATED; 01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00574
Associated ProRule [info]	PRU00221

Name and characterization of the entry

Description [info]	Trp-Asp (WD) repeats signature.
Pattern [info]	[LIVMSTAC]-[LIVMFYWSTAGC]-[LIMSTAG]-[LIVMSTAGC]-x(2)-[DN]-x-{P}- [LIVMWSTAC]-{DP}-[LIVMFSTAG]-W-[DEN]-[LIVMFSTAGCN].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	3'481 in 1'870 different sequences
Number of true positive hits	3'236 in 1'625 different sequences
Number of 'unknown' hits	0
Number of false positive hits	245 in 245 different sequences
Number of false negative sequences	989
Number of 'partial' sequences	1

Precision (true positives / (true positives + false positives))	92.96 %
Recall (true positives / (true positives + false negatives))	76.59 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info]	11
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	1625 sequences 2AB1_CAEEL (G5EDR3), 2ABA_ARATH (Q38821), 2ABA_CANTR (P53031), » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	989 sequences 2ABA_DROME (P36872), 2ABA_HUMAN (P63151), 2ABA_MACFA (Q4R7Z4), » more
UniProtKB/Swiss-Prot 'Partial' sequences	1 sequence NBEA_CHICK (Q9DDD5)
UniProtKB/Swiss-Prot False positive sequences	245 sequences ACSA_RHOBA (P59872), AGO_SYNE7 (Q31N05), APDD_EMENI (Q5ATH0), » more
PDB [Detailed view]	2534 PDB 1A0R; 1B9X; 1B9Y; 1ERJ; 1GG2; 1GOT; 1GP2; 1GXR; 1NEX; 1NR0; 1OMW; 1P22; » more