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PROSITE entry PS00671


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00671
Entry name [info] D_2_HYDROXYACID_DH_3
Accession [info] PS00671
Entry type [info] PATTERN
Date [info] 01-JUN-1992 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00063

Name and characterization of the entry

Description [info] D-isomer specific 2-hydroxyacid dehydrogenases signature 3.
Pattern [info] 
[LMFATCYV]-[KPQNHAR]-x-[GSTDNK]-x-[LIVMFYWRC]-[LIVMFYW](2)-N-x-[STAGC]-R-
[GP]-x-[LIVH]-[LIVMCT]-[DNVE].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 333 in 333 different sequences
Number of true positive hits 332 in 332 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 69
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 99.70 %
Recall (true positives / (true positives + false negatives)) 82.79 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 332 sequences 

CTBP1_HUMAN (Q13363), CTBP1_MOUSE (O88712), CTBP1_RAT   (Q9Z2F5),
» more

UniProtKB/Swiss-Prot
False negative sequences		 69 sequences 

2KGR_GLUOX  (Q5FTU6), CTBP1_CAEEL (Q20595), CTBP_ARATH  (O23702),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

YMP5_STRCH  (P43169)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			1 sequence
			


			
VF030_IIV3  (Q196V4)


				
	

	

		PDB
[Detailed view]		
		
			96 PDB
			


			1DXY; 1GDH; 1HKU; 1HL3; 1J49; 1J4A; 1MX3; 1PSD; 1SC6; 1YBA; 1YGY; 2DBQ; 
			
			

			» more