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Entry: PS00670

General information about the entry
Entry nameD_2_HYDROXYACID_DH_2
Accession numberPS00670
Entry typePATTERN
DateJUN-1992 (CREATED); JUL-1998 (DATA UPDATE); NOV-2008 (INFO UPDATE).
PROSITE DocumentationPDOC00063
Name and characterization of the entry
DescriptionD-isomer specific 2-hydroxyacid dehydrogenases signature 2.
Pattern[LIVMFYWA]-[LIVFYWC]-x(2)-[SAC]-[DNQHR]-[IVFA]-[LIVF]-x-[LIVF]-[HNI]-x- P-x(4)-[STN]-x(2)-[LIVMF]-x-[GSDN].
Numerical results
  • UniProtKB/Swiss-Prot release number: 56.6, total number of sequence entries in that release: 405506.
  • Total number of hits in UniProtKB/Swiss-Prot: 100 hits in 100 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 100 hits in 100 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 0 hits in 0 different sequences
  • Number of known missed hits: 185
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 1
  • Precision (true hits / (true hits + false positives)): 100.00 %
  • Recall (true hits / (true hits + false negatives)): 35.09 %
Comments
  • Taxonomic range: Archaebacteria, Eukaryotes, Prokaryotes (Bacteria)
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • VERSION: 1
Cross-references
UniProtKB/Swiss-ProtTrue positive hits:
DDH1_SCHPO  (Q9P7P8), DDH2_SCHPO  (Q9P7Q1), DDH_HAEIN   (P44501), 
DDH_ZYMMO   (P30799), DHD2_LACPA  (P17584), DHGY_HYPME  (P36234), 
DHGY_METEX  (Q59516), FDH1_ORYSJ  (Q9SXP2), FDH1_YEAST  (Q08911), 
FDH2_ORYSJ  (Q67U69), FDH2_YEAST  (Q08987), FDH_ARATH   (Q9S7E4), 
FDH_EMENI   (Q03134), FDH_HORVU   (Q9ZRI8), FDH_NEUCR   (Q07103), 
FDH_PICAN   (P33677), FDH_PSESR   (P33160), FDH_SOLTU   (Q07511), 
GHRB_CITK8  (A8ARD9), GHRB_ECO24  (A7ZTA0), GHRB_ECO57  (P58220), 
GHRB_ECODH  (B1X8G8), GHRB_ECOHS  (A8A609), GHRB_ECOK1  (A1AH96), 
GHRB_ECOL5  (Q0TBP9), GHRB_ECOL6  (Q8FCF1), GHRB_ECOLC  (B1IZP1), 
GHRB_ECOLI  (P37666), GHRB_ECOSM  (B1LJB3), GHRB_ECOUT  (Q1R543), 
GHRB_ENTS8  (A7MKR1), GHRB_KLEP7  (A6TFG7), GHRB_SALCH  (Q57IH8), 
GHRB_SALPA  (Q5PLL9), GHRB_SALPB  (A9MUT4), GHRB_SALTI  (Q8Z2A8), 
GHRB_SALTY  (Q8ZLA1), GHRB_SHIB3  (B2U573), GHRB_SHIBS  (Q31V71), 
GHRB_SHIDS  (Q328L4), GHRB_SHIF8  (Q0SZE5), GHRB_SHIFL  (Q83PR3), 
GHRB_SHISS  (Q3YVT5), GYAR_AERPE  (Q9YAW4), GYAR_KORCO  (B1L765), 
GYAR_THELI  (Q9C4M5), GYAR_THEPD  (A1RYE4), LDHD_DICDI  (Q54UF7), 
LDHD_ECOLI  (P52643), LDHD_LACDA  (P26297), LDHD_LACHE  (P30901), 
LDHD_LACPE  (P26298), LDHD_LACPL  (Q88VJ2), LDHD_PEDAC  (Q59642), 
LDHD_STAAC  (Q5HD29), LDHD_STAAM  (P63940), LDHD_STAAN  (P99116), 
LDHD_STAAR  (Q6GDS2), LDHD_STAAS  (Q6G6F1), LDHD_STAAU  (P72357), 
LDHD_STAAW  (Q8NUT2), LDHD_STAEQ  (Q5HLA0), LDHD_STAES  (Q8CN22), 
LDHD_TREPA  (O83080), PDXB_PSEMY  (A4XTK4), SER33_YEAST (P40510), 
SERA_ARATH  (O04130), SERA_ARCFU  (O29445), SERA_BACSU  (P35136), 
SERA_BOVIN  (Q5EAD2), SERA_DICDI  (Q54UH8), SERA_ECO57  (P0A9T2), 
SERA_ECOL6  (P0A9T1), SERA_ECOLI  (P0A9T0), SERA_HAEIN  (P43885), 
SERA_HUMAN  (O43175), SERA_MACFA  (Q60HD7), SERA_METJA  (Q58424), 
SERA_METTH  (O27051), SERA_MOUSE  (Q61753), SERA_MYCBO  (P0A545), 
SERA_MYCLE  (O33116), SERA_MYCTU  (P0A544), SERA_PANTR  (A5A6P1), 
SERA_PIG    (A5GFY8), SERA_PONAB  (Q5R7M2), SERA_RAT    (O08651), 
SERA_SCHPO  (P87228), SERA_SHIFL  (P0A9T3), SERA_SYNY3  (P73821), 
SERA_YEAST  (P40054), TKRA_BACSU  (O32264), VANH_ENTFA  (Q47748), 
VANH_ENTFC  (Q05709), Y1556_HAEIN (P45250), Y2355_CORGL (P0C1E8), 
YEAA_SCHPO  (O14075), YGDH_SCHPO  (O94574), YN14_YEAST  (P53839), 
YPRB2_CORML (P0C1E9)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
CTBP1_HUMAN (Q13363), CTBP1_MOUSE (O88712), CTBP1_RAT   (Q9Z2F5), 
CTBP1_XENLA (Q9YHU0), CTBP2_BOVIN (Q0VCQ1), CTBP2_HUMAN (P56545), 
CTBP2_MOUSE (P56546), CTBP2_RAT   (Q9EQH5), CTBP2_XENLA (Q9W758), 
CTBP_DROME  (O46036), DHGY_CUCSA  (P13443), GHRA_CITK8  (A8AI49), 
GHRA_ECO57  (Q8X9K1), GHRA_ECODH  (B1X9E7), GHRA_ECOHS  (A7ZYY6), 
GHRA_ECOK1  (A1A9T1), GHRA_ECOL5  (Q0TJ41), GHRA_ECOL6  (Q8FIT1), 
GHRA_ECOLC  (B1IV68), GHRA_ECOLI  (P75913), GHRA_ECOSM  (B1LIY1), 
GHRA_ECOUT  (Q1RDC8), GHRA_ENT38  (A4W948), GHRA_ENTS8  (A7MFZ8), 
GHRA_KLEP7  (A6T7B8), GHRA_PHOLL  (Q7N571), GHRA_SALAR  (A9MH27), 
GHRA_SALCH  (Q57QM2), GHRA_SALPA  (Q5PGZ3), GHRA_SALPB  (A9N5T3), 
GHRA_SALTI  (Q8Z7M6), GHRA_SALTY  (Q8ZQ30), GHRA_SERP5  (A8GD46), 
GHRA_SHIB3  (B2TTN6), GHRA_SHIBS  (Q31Z89), GHRA_SHIDS  (Q32HN5), 
GHRA_SHISS  (Q3Z393), GHRA_YERE8  (A1JRR3), GHRB_ENT38  (A4W577), 
GHRB_ENTAG  (P58000), GHRB_ERWCT  (Q6DB24), GHRB_SERP5  (A8G7S7), 
GHRB_YERE8  (A1JT62), GHRB_YERP3  (A7FPA2), GHRB_YERPA  (Q1C3K4), 
GHRB_YERPB  (B2K7F1), GHRB_YERPE  (Q0W9V5), GHRB_YERPG  (A9R4G6), 
GHRB_YERPN  (Q1CD80), GHRB_YERPP  (A4TGN1), GHRB_YERPS  (Q663W4), 
GHRB_YERPY  (B1JH01), GRHPR_HUMAN (Q9UBQ7), GRHPR_MOUSE (Q91Z53), 
GYAR_PYRAB  (Q9UYR1), GYAR_PYRFU  (Q8U3Y2), GYAR_PYRHO  (O58320), 
GYAR_PYRKO  (Q5JEZ2), LDHD_LEUMC  (P51011), LDHD_STRA3  (Q8E6A9), 
LDHD_STRA5  (Q8E0N5), LDHD_STRP1  (Q99ZM2), PDXB_ACIAD  (Q6F943), 
PDXB_ACIBT  (A3M810), PDXB_AERHH  (A0KLP0), PDXB_AERS4  (A4SNU1), 
PDXB_ALCBS  (Q0VQC3), PDXB_BACFN  (Q5LIR8), PDXB_BACFR  (Q64ZV5), 
PDXB_BACTN  (Q8A2E4), PDXB_BAUCH  (Q1LTA7), PDXB_BLOFL  (Q7VRU9), 
PDXB_BLOPB  (Q492H2), PDXB_CHRSD  (Q1QXV7), PDXB_CITK8  (A8ADQ9), 
PDXB_COLP3  (Q47XK1), PDXB_COXBN  (A9KEY5), PDXB_COXBR  (A9NAQ7), 
PDXB_COXBU  (Q83AR8), PDXB_ECO24  (A7ZPD6), PDXB_ECO57  (Q8XCR0), 
PDXB_ECOHS  (A8A2I9), PDXB_ECOK1  (A1ADG9), PDXB_ECOL5  (Q0TFC6), 
PDXB_ECOL6  (Q8FFH2), PDXB_ECOLC  (B1IXM2), PDXB_ECOLI  (P05459), 
PDXB_ECOUT  (Q1R992), PDXB_ENT38  (A4WCV4), PDXB_ENTS8  (A7MH63), 
PDXB_ERWCT  (Q6D2N5), PDXB_HAHCH  (Q2SJQ9), PDXB_IDILO  (Q5QUE2), 
PDXB_LEGPA  (Q5X6I6), PDXB_LEGPH  (Q5ZX15), PDXB_LEGPL  (Q5WXZ0), 
PDXB_MARAV  (A1U1I8), PDXB_MARMS  (A6VXM3), PDXB_PHOLL  (Q7N2B2), 
PDXB_PHOPR  (Q6LNU2), PDXB_PORGI  (Q7MV70), PDXB_PSE14  (Q48KQ3), 
PDXB_PSEA6  (Q15QG8), PDXB_PSEA7  (A6V8H9), PDXB_PSEAB  (Q02JM2), 
PDXB_PSEAE  (Q9I3W9), PDXB_PSEE4  (Q1I7B3), PDXB_PSEF5  (Q4KFD1), 
PDXB_PSEHT  (Q3IF36), PDXB_PSEP1  (A5W6I8), PDXB_PSEPF  (Q3K9D1), 
PDXB_PSEPG  (B0KGD9), PDXB_PSEPK  (Q88L20), PDXB_PSESM  (Q884R9), 
PDXB_PSEU2  (Q4ZVE7), PDXB_PSEU5  (A4VKJ1), PDXB_PSYA2  (Q4FV16), 
PDXB_PSYCK  (Q1QE21), PDXB_PSYIN  (A1SW94), PDXB_PSYWF  (A5WHK7), 
PDXB_RUTMC  (A1AWW7), PDXB_SACD2  (Q21LK8), PDXB_SALAR  (A9MJ55), 
PDXB_SALCH  (Q57LY4), PDXB_SALPA  (Q5PCV8), PDXB_SALPB  (A9N474), 
PDXB_SALRD  (Q2S0U3), PDXB_SALTI  (P60801), PDXB_SALTY  (P60802), 
PDXB_SERP5  (A8GH44), PDXB_SHEAM  (A1S7K2), PDXB_SHEB5  (A3D669), 
PDXB_SHEB8  (A6WQ07), PDXB_SHEB9  (A9KTV0), PDXB_SHEDO  (Q12P58), 
PDXB_SHEFN  (Q084S1), PDXB_SHEHH  (B0TKZ7), PDXB_SHELP  (A3QFC7), 
PDXB_SHEON  (Q8ECR2), PDXB_SHEPC  (A4Y882), PDXB_SHESA  (A0KV91), 
PDXB_SHESH  (A8FTT7), PDXB_SHESM  (Q0HKB6), PDXB_SHESP  (Q56731), 
PDXB_SHESR  (Q0HWL8), PDXB_SHESW  (A1RIA7), PDXB_SHEVI  (Q56733), 
PDXB_SHIBS  (Q31YD8), PDXB_SHIDS  (Q32DL6), PDXB_SHIF8  (Q0T2G5), 
PDXB_SHIFL  (Q83QR1), PDXB_SHISS  (Q3YZP1), PDXB_SODGM  (Q2NSH9), 
PDXB_THICR  (Q31IH6), PDXB_VESOH  (A5CWD1), PDXB_VIBCH  (Q9KQ92), 
PDXB_VIBF1  (Q5E452), PDXB_VIBPA  (Q87MN8), PDXB_VIBVU  (Q8DB36), 
PDXB_VIBVY  (Q7MIT6), PDXB_WIGBR  (Q8D2P6), PDXB_YERE8  (A1JL55), 
PDXB_YERP3  (A7FGL9), PDXB_YERPA  (Q1C676), PDXB_YERPE  (Q8D0U3), 
PDXB_YERPN  (Q1CHL8), PDXB_YERPP  (A4TM66), PDXB_YERPS  (Q668W7), 
PTXD_PSEST  (O69054), TKRA_DICDI  (Q54DP1), Y1879_STAES (Q8CNB8), 
Y1888_STAEQ (Q5HLU4), Y2098_STAAN (Q7A417), Y2178_STAAB (Q2YYT9), 
Y2196_STAAS (Q6G716), Y2224_STAAW (Q8NV80), Y2254_STAA3 (Q2FEI9), 
Y2296_STAAC (Q5HDQ4), Y2305_STAAM (Q99RW8), Y2389_STAAR (Q6GEC9), 
Y2577_STAA8 (Q2FVW4), Y606_STAS1  (Q49ZM5), Y752_STAHJ  (Q4L8G4), 
YGT5_YEAST  (P53100), YP113_YEAST (Q02961)
`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences):
YMP5_STRCO  (P43169)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]
1DLD; 1DXY; 1GDH; 1J49; 1J4A; 1PSD; 1YGY; 2DLD; 2G76; 2GO1; 2GUG; 2NAC; 2NAD; 2P9C; 2P9E; 2P9G; 2PA3; 3DC2; 3DDN;

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View entry in raw text format (no links)
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