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PROSITE entry PS00633


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00633
Entry name [info] BROMODOMAIN_1
Accession [info] PS00633
Entry type [info] PATTERN
Date [info] 01-JUN-1992 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00550

Name and characterization of the entry

Description [info] Bromodomain signature.
Pattern [info] 
[STANVFHG]-x(2)-[FAS]-x(4)-[DNSPAKT]-x(0,7)-[DENQTFG]-Y-[HFYLRKT]-x(2)-
[LIVMFY]-x(3)-[LIVM]-x(4)-[LIVM]-x(6,10)-Y-x(12,13)-[LIVM]-x(2)-N-[SACF]-
x(2)-[FY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 149 in 116 different sequences
Number of true positive hits 149 in 116 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 55
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 73.04 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 5
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 116 sequences 

ATD2B_HUMAN (Q9ULI0), BAZ1A_HUMAN (Q9NRL2), BAZ1A_MOUSE (O88379),
» more

UniProtKB/Swiss-Prot
False negative sequences		 55 sequences 

ASH1L_HUMAN (Q9NR48), ASH1L_MOUSE (Q99MY8), ATAD2_HUMAN (Q6PL18),
» more

PDB
[Detailed view]		 1974 PDB

1E6I; 1EQF; 1F68; 1JM4; 1JSP; 1N72; 1WUG; 1WUM; 1X0J; 1ZS5; 2D82; 2D9E;
» more