PROSITE entry PS00509
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PURL: https://purl.expasy.org/prosite/signature/PS00509
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General information about the entry
| Entry name [info] | RAS_GTPASE_ACTIV_1 |
| Accession [info] | PS00509 |
| Entry type [info] | PATTERN |
| Date [info] |
01-MAY-1991 CREATED;
01-DEC-2004 DATA UPDATE; 18-JUN-2025 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00438 |
Name and characterization of the entry
| Description [info] | Ras GTPase-activating proteins (rasGAP) domain signature. |
| Pattern [info] |
[GSNA]-x-[LIVMF]-[FYCI]-[LIVMFY]-R-[LIVMFY](2)-[GACNS]-[PAV]-[AV]-[LIV]- [LIVM]-[SGANT]-P. |
Numerical results [info]
| Total number of hits | 43 in 43 different sequences |
| Number of true positive hits | 43 in 43 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 13 |
| Number of 'partial' sequences | 1 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 76.79 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
43 sequences
BUD2_CANAL (Q5A506), BUD2_YEAST (P33314), DAB2P_HUMAN (Q5VWQ8),» more
|
| UniProtKB/Swiss-Prot False negative sequences |
13 sequences
GAPA_DICDI (O00899), GAPD1_BOVIN (A5D794), GAPD1_HUMAN (Q14C86),» more |
| UniProtKB/Swiss-Prot 'Partial' sequences |
1 sequence
NF1_CHICK (P35608) |
| PDB [Detailed view] |
28 PDB
1NF1; 1WER; 1WQ1; 3BXJ; 3FAY; 5CJP; 6OB2; 6OB3; 6V65; 6V6F; 7MOC; 7MP5; » more |