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Entry: PS00501

General information about the entry
Entry nameSPASE_I_1
Accession numberPS00501
Entry typePATTERN
DateMAY-1991 (CREATED); DEC-2004 (DATA UPDATE); FEB-2010 (INFO UPDATE).
PROSITE DocumentationPDOC00418
Associated ProRulePRU10097
Name and characterization of the entry
DescriptionSignal peptidases I serine active site.
Pattern[GS]-{PR}-S-M-{RS}-[PS]-[AT]-[LF].
Numerical results
  • UniProtKB/Swiss-Prot release number: 57.15, total number of sequence entries in that release: 515203.
  • Total number of hits in UniProtKB/Swiss-Prot: 109 hits in 109 different sequences
  • Number of hits on proteins that are known to belong to the set under consideration: 53 hits in 53 different sequences
  • Number of hits on proteins that could potentially belong to the set under consideration: 0 hits in 0 different sequences
  • Number of false hits (on unrelated proteins): 56 hits in 56 different sequences
  • Number of known missed hits: 20
  • Number of partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences: 0
  • Precision (true hits / (true hits + false positives)): 48.62 %
  • Recall (true hits / (true hits + false negatives)): 72.60 %
Comments
  • Taxonomic range: Eukaryotes, Prokaryotes (Bacteria)
  • Maximum known number of repetitions of the pattern in a single protein: 1
  • `Interesting' site in the pattern: 3,active_site
  • VERSION: 1
Cross-references
UniProtKB/Swiss-ProtTrue positive hits:
IMP1_YEAST  (P28627), IMP2_YEAST  (P46972), LEP1_BACAM  (P41026), 
LEP1_SYNY3  (P72660), LEP2_BACAM  (P41025), LEP2_SYNY3  (P73157), 
LEPP_BACNA  (P37943), LEPQ_BACNA  (Q57350), LEPS_BACSU  (P28628), 
LEPT_BACSU  (P71013), LEPU_BACSU  (P42959), LEPV_BACSU  (O07560), 
LEP_AQUAE   (O67088), LEP_BACCL   (P41027), LEP_BACLI   (P42668), 
LEP_BUCAI   (P57347), LEP_BUCAP   (Q8K9R0), LEP_BUCBP   (Q89AM6), 
LEP_ECOLI   (P00803), LEP_HAEIN   (P44454), LEP_MYCLE   (O33021), 
LEP_MYCTU   (Q10789), LEP_PHOLA   (Q51876), LEP_PSEAE   (Q9I5G7), 
LEP_PSEFL   (P26844), LEP_SALTI   (P0A1W3), LEP_SALTY   (P0A1W2), 
LEP_STAAC   (Q5HHB9), LEP_STAAM   (P0A067), LEP_STAAN   (P0A068), 
LEP_STAAR   (Q6GIC3), LEP_STAAS   (Q6GAW1), LEP_STAAU   (P0A070), 
LEP_STAAW   (P0A069), LEP_STRPN   (O07344), LEP_STRR6   (P59662), 
PLSP1_ARATH (Q8H0W1), SC11A_BOVIN (P67810), SC11A_CANFA (P67811), 
SC11A_HUMAN (P67812), SC11A_MOUSE (Q9R0P6), SC11A_PONAB (Q5R9C7), 
SC11A_RAT   (P42667), SC11B_HUMAN (P0C7V7), SC11C_CANFA (P13679), 
SC11C_HUMAN (Q9BY50), SC11C_MOUSE (Q9D8V7), SC11C_PONAB (Q5RC30), 
SC11C_RAT   (Q9WTR7), SEC11_DICDI (Q86JD4), SEC11_YEAST (P15367), 
TPP1_ARATH  (O04348), TPP2_ARATH  (Q9M9Z2)
False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile):
IMP1L_HUMAN (Q96LU5), IMP1L_MOUSE (Q9CQU8), IMP1L_XENTR (Q28I39), 
IMP2L_BOVIN (Q2KI92), IMP2L_DANRE (Q6AZD4), IMP2L_HUMAN (Q96T52), 
IMP2L_MOUSE (Q8BPT6), IMP2L_SCHPO (Q9UST2), IMP2L_XENLA (Q5PQ63), 
LEPH_STAAC  (Q5HHC0), LEPH_STAAM  (P0A063), LEPH_STAAN  (P0A064), 
LEPH_STAAR  (Q6GIC4), LEPH_STAAS  (Q6GAW2), LEPH_STAAU  (P0A066), 
LEPH_STAAW  (P0A065), LEP_HELPJ   (Q9ZLQ5), LEP_HELPY   (O25300), 
LEP_RICCN   (Q92JB1), LEP_RICPR   (Q9ZE32)
False positive hits (sequences which do not belong to the set under consideration):
ALDO1_ARATH (Q7G193), AQPZ_ECO57  (Q8X6K6), AQPZ_ECOL6  (P60845), 
AQPZ_ECOLI  (P60844), AQPZ_SHIFL  (O68874), ATG12_ASPCL (A1CTJ1), 
ATG12_ASPFU (A4D9P4), ATG12_ASPOR (Q2UMW6), ATG12_COCIM (Q1E8C2), 
ATG12_MAGGR (Q51P78), ATG12_NEOFI (A1DMW6), CDKL5_HUMAN (O76039), 
DDL_SYNPW   (A5GML7), FREM1_HUMAN (Q5H8C1), GNL3L_BOVIN (Q3T0J9), 
GNL3L_HUMAN (Q9NVN8), LVSD_DICDI  (Q55AV3), L_CHAVB     (B2C4J3), 
NAGA_HUMAN  (Q9Y303), NFAA_DICDI  (Q55AR6), O51S1_HUMAN (Q8NGJ8), 
PEPF1_LACLC (P54124), PEPF_LACLA  (Q9CEV7), PLSX_PARDP  (A1B363), 
PLSX_SILST  (Q1GI68), PPE19_MYCTU (Q11031), PR2_DROME   (Q9I7F7), 
RIMB2_MOUSE (Q80U40), RIMB2_RAT   (Q9JIR1), RS9_STRCO   (Q53875), 
SNT2_YEAST  (P53127), STU1_SCHPO  (O42874), TBB1_AVESA  (P25862), 
TBB1_ORYSJ  (Q43594), TBB1_WHEAT  (Q9ZRB2), TBB2_ELEIN  (Q9ZPN9), 
TBB2_WHEAT  (Q9ZRB1), TBB3_GOSHI  (Q6VAF8), TBB3_PEA    (P29502), 
TBB4_ELEIN  (Q9ZPN7), TBB4_ORYSJ  (P45960), TBB5_MAIZE  (Q43697), 
TBB5_WHEAT  (Q9ZRA8), TBB6_ARATH  (P29514), TBB6_MAIZE  (Q41783), 
TBB6_ORYSJ  (Q76FS3), TBB8_MAIZE  (Q41785), TBB8_ORYSJ  (Q76FS2), 
TBB_HORVU   (P93176), TPIS_GRAVE  (P48492), TPO5_YEAST  (P36029), 
UPP3_SCHPO  (Q9US43), WD51A_MOUSE (Q8JZX3), Y017_OSHV1  (Q6R7K6), 
ZN598_DANRE (Q6PFK1), ZN643_HUMAN (Q9UJL9)
Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:

[Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format]

Retrieve the sequence logo from the alignment

PDB
[Detailed view]		1B12; 1KN9; 1T7D; 3IIQ;

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