PROSITE logo

PROSITE entry PS00501


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00501
Entry name [info] SPASE_I_1
Accession [info] PS00501
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00418
Associated ProRule [info] PRU10097

Name and characterization of the entry

Description [info] Signal peptidases I serine active site.
Pattern [info] 
[GS]-{PR}-S-M-{RS}-[PS]-[AT]-[LF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 185 in 185 different sequences
Number of true positive hits 121 in 121 different sequences
Number of 'unknown' hits 1
Number of false positive hits 63 in 63 different sequences
Number of false negative sequences 21
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 65.76 %
Recall (true positives / (true positives + false negatives)) 85.21 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 121 sequences 

IMP1_YEAST  (P28627), IMP2_YEAST  (P46972), LEP1_BACAM  (P41026),
» more

UniProtKB/Swiss-Prot
False negative sequences		 21 sequences 

IMP1L_HUMAN (Q96LU5), IMP1L_MOUSE (Q9CQU8), IMP1L_XENTR (Q28I39),
» more

UniProtKB/Swiss-Prot
'Unknown' sequences		 1 sequence 

L_CHAVB (B2C4J3)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			63 sequences
			


			
ACKL_DROME  (Q9I7F7), ALDO1_ARATH (Q7G193), AQPZ_ECO57  (Q8X6K6), 

			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			11 PDB
			


			1B12; 1KN9; 1T7D; 3IIQ; 3S04; 4WVH; 4WVI; 4WVJ; 6B88; 7P2P; 7P2Q