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PROSITE entry PS00487


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PURL: https://purl.expasy.org/prosite/signature/PS00487

Direct ScanProsite submission
General information about the entry

Entry name [info] IMP_DH_GMP_RED
Accession [info] PS00487
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00391

Name and characterization of the entry

Description [info] IMP dehydrogenase / GMP reductase signature.
Pattern [info]
[LIVMT]-[RK]-[LIVM]-G-[LIVM]-G-x-G-[SRK]-[LIVMAT]-C-x-T.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 280 in 280 different sequences
Number of true positive hits 280 in 280 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.29 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] IMP_binding(?) at position 11
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
280 sequences

GMPR1_HUMAN (P36959), GMPR1_MOUSE (Q9DCZ1), GMPR1_RAT   (Q9Z244), 
» more

UniProtKB/Swiss-Prot
False negative sequences
2 sequences

GUAC_CHRVO  (Q7NTY1), GUAC_MYCMS  (Q6MUI1)

		
PDB
[Detailed view]
92 PDB

1AK5; 1B3O; 1EEP; 1JCN; 1JR1; 1LRT; 1ME7; 1ME8; 1ME9; 1MEH; 1MEI; 1MEW;
» more