PROSITE entry PS00486

View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission

General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00486
Entry name [info]	DNA_MISMATCH_REPAIR_2
Accession [info]	PS00486
Entry type [info]	PATTERN
Date [info]	01-MAY-1991 CREATED; 01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00388

Name and characterization of the entry

Description [info]	DNA mismatch repair proteins mutS family signature.
Pattern [info]	[STA]-[LIVMF]-x-[LIVM]-x-D-E-[LIVMFY]-[GCA]-[RKHAS]-[GS]-[GST]-x(4)-G.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	803 in 803 different sequences
Number of true positive hits	803 in 803 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	13
Number of 'partial' sequences	1

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	98.41 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	803 sequences HEXA_STRPN (P0A3R3), HEXA_STRR6 (P0A3R4), HIM14_CAEEL (Q23405), » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	13 sequences MUTS2_ANADF (A7HAB8), MUTS2_CARHZ (Q3ABU1), MUTS2_CLOBA (B2V583), » more
UniProtKB/Swiss-Prot 'Partial' sequences	1 sequence MUTS_YEREN (P47763)
PDB [Detailed view]	58 PDB 1E3M; 1EWQ; 1EWR; 1FW6; 1NG9; 1NNE; 1OH5; 1OH6; 1OH7; 1OH8; 1W7A; 1WB9; » more