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PROSITE entry PS00485


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00485
Entry name [info] A_DEAMINASE
Accession [info] PS00485
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00419
Associated ProRule [info] PRU10104

Name and characterization of the entry

Description [info] Adenosine and AMP deaminase signature.
Pattern [info] 
[SA]-[LIVM]-[NGS]-[STA]-D-D-P.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 110 in 110 different sequences
Number of true positive hits 89 in 89 different sequences
Number of 'unknown' hits 0
Number of false positive hits 21 in 21 different sequences
Number of false negative sequences 97
Number of 'partial' sequences 3
Precision (true positives / (true positives + false positives)) 80.91 %
Recall (true positives / (true positives + false negatives)) 47.85 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site(?) at position 5
Site [info] active_site(?) at position 6
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 89 sequences 

ADA_BOVIN   (P56658), ADA_CHICK   (Q5ZKP6), ADA_DANRE   (Q6DG22),
» more

UniProtKB/Swiss-Prot
False negative sequences		 97 sequences 

ADA2_DANRE  (P58781), ADA2_DICDI  (Q553U5), ADA2_HUMAN  (Q9NZK5),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 3 sequences 

ADA2_CHICK  (P84520), AMPD1_CHICK (P81073), AMPD1_RABIT (P81072)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			21 sequences
			


			
AGRV1_HUMAN (Q8WXG9), CH60_SYNWW  (Q0AVV1), CYCH_BRADU  (P45399), 

			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			38 PDB
			


			1A4L; 1A4M; 1ADD; 1KRM; 1NDV; 1NDW; 1NDY; 1NDZ; 1O5R; 1QXL; 1UIO; 1UIP; 
			
			

			» more