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PROSITE entry PS00470


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00470
Entry name [info] IDH_IMDH
Accession [info] PS00470
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00389

Name and characterization of the entry

Description [info] Isocitrate and isopropylmalate dehydrogenases signature.
Pattern [info]
[NSK]-[LIMYTV]-[FYDNH]-[GEA]-[DNGSTY]-[IMVYL]-x-[STGDN]-[DN]-x(1,2)-
[SGAP]-x(3,4)-[GE]-[STG]-[LIVMPA]-[GA]-[LIVMF].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 408 in 408 different sequences
Number of true positive hits 407 in 407 different sequences
Number of 'unknown' hits 1
Number of false positive hits 0
Number of false negative sequences 9
Number of 'partial' sequences 6
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.84 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
407 sequences

AKSF_METJA  (Q58991), AMT6_ALTAL  (C9K7B7), DLPA_LEGPH  (Q48806), 
» more

UniProtKB/Swiss-Prot
False negative sequences
9 sequences

IDH1_ARATH  (Q8LFC0), IDH2_ARATH  (P93032), IDH3_ARATH  (O81796), 
» more

UniProtKB/Swiss-Prot
'Partial' sequences
6 sequences

IDH3A_CANLF (P54836), IDH3A_MESAU (P86225), IDH3B_PIG   (P56472), 
» more

UniProtKB/Swiss-Prot
'Unknown' sequences
1 sequence

IDH3A_PIG   (P56471)

		
PDB
[Detailed view]
194 PDB

1A05; 1AI2; 1AI3; 1BL5; 1CM7; 1CNZ; 1CW1; 1CW4; 1CW7; 1DPZ; 1DR0; 1DR8;
» more