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PROSITE entry PS00469


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PURL: https://purl.expasy.org/prosite/signature/PS00469

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General information about the entry

Entry name [info] NDPK
Accession [info] PS00469
Entry type [info] PATTERN
Date [info] 01-MAY-1991 CREATED;
01-JUL-1999 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00409
Associated ProRule [info] PRU10030

Name and characterization of the entry

Description [info] Nucleoside diphosphate kinase (NDPK) active site signature.
Pattern [info] 
N-x(2)-H-[GA]-S-D-[GSA]-[LIVMPKNE].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 606 in 606 different sequences
Number of true positive hits 598 in 598 different sequences
Number of 'unknown' hits 0
Number of false positive hits 8 in 8 different sequences
Number of false negative sequences 131
Number of 'partial' sequences 15
Precision (true positives / (true positives + false positives)) 98.68 %
Recall (true positives / (true positives + false negatives)) 82.03 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 598 sequences 

NDK1_ARATH  (P39207), NDK1_MAIZE  (B4FK49), NDK1_MESCR  (O81372),
» more

UniProtKB/Swiss-Prot
False negative sequences		 131 sequences 

NDK1_PARUW  (Q6MEA9), NDK2_PARUW  (Q6MEA7), NDK7_BOVIN  (Q5E9Y9),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 15 sequences 

NDK1_PSEMZ  (P85929), NDK2_PSEMZ  (P85930), NDKB_MACMG  (P85292),
» more

UniProtKB/Swiss-Prot
False positive sequences		 8 sequences 

GLO2_ROSDO  (Q162S3), MDM10_PARBA (C1GVA2), OTU7_ARATH  (F4K3M6),
» more

PDB
[Detailed view]		 116 PDB

1B99; 1BE4; 1BHN; 1BUX; 1EHW; 1F6T; 1HHQ; 1HIY; 1JXV; 1KDN; 1LEO; 1NCL;
» more