PROSITE entry PS00460
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PURL: https://purl.expasy.org/prosite/signature/PS00460
Direct ScanProsite submission
General information about the entry
| Entry name [info] | GLUTATHIONE_PEROXID_1 |
| Accession [info] | PS00460 |
| Entry type [info] | PATTERN |
| Date [info] |
01-MAY-1991 CREATED;
01-JAN-2008 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00396 |
Name and characterization of the entry
| Description [info] | Glutathione peroxidases active site. |
| Pattern [info] |
[GNDRC]-[RKHNQFYCS]-x-[LIVMFCS]-[LIVMF](2)-x-N-[VT]-x-[STCA]-x-[CU]- [GA]-x-[TA]. |
Numerical results [info]
| Total number of hits | 97 in 97 different sequences |
| Number of true positive hits | 97 in 97 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 0 |
| Number of false negative sequences | 15 |
| Number of 'partial' sequences | 1 |
| Precision (true positives / (true positives + false positives)) | 100.00 % |
| Recall (true positives / (true positives + false negatives)) | 86.61 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Site [info] | active_site at position 12 |
| Version [info] | 2 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
97 sequences
BSAA_BACSU (P52035), BSAA_HALH5 (Q9Z9N7), BTUE_ECOLI (P06610),» more
|
| UniProtKB/Swiss-Prot False negative sequences |
15 sequences
BSAA_STAAC (Q5HGC7), BSAA_STAAM (P64290), BSAA_STAAN (P99097),» more |
| UniProtKB/Swiss-Prot 'Partial' sequences |
1 sequence
GPX4_PINPS (P81087) |
| PDB [Detailed view] |
28 PDB
1GP1; 2HE3; 2I3Y; 2OBI; 2P31; 2V1M; 3CMI; 5H5Q; 5H5R; 5H5S; 5L71; 6ELW; » more |