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PROSITE entry PS00433


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00433
Entry name [info] PHOSPHOFRUCTOKINASE
Accession [info] PS00433
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00336

Name and characterization of the entry

Description [info] Phosphofructokinase signature.
Pattern [info] 
[RK]-x(4)-[GAS]-H-x-[QL]-[QR]-[GS]-[GF]-x(5)-[DE]-[RL].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 340 in 303 different sequences
Number of true positive hits 340 in 303 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 17
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 95.24 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] substrate_binding at position 1
Site [info] substrate_binding at position 4
Site [info] substrate_binding at position 7
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 303 sequences 

PFKA1_ASPOR (Q9HGZ1), PFKA1_BACTN (Q8A8R5), PFKA1_CAEEL (Q9TZL8),
» more

UniProtKB/Swiss-Prot
False negative sequences		 17 sequences 

PFKA1_CLOPE (Q8XNH2), PFKA3_BACTN (Q8A2E9), PFKA_ENTFA  (Q836R3),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

PFKA2_THET8 (P21778), PFKA_CALFI  (Q27543)


				
	

	

		PDB
[Detailed view]		
		
			34 PDB
			


			1MTO; 1PFK; 1ZXX; 2PFK; 3O8L; 3O8N; 3O8O; 3OPY; 3PFK; 3U39; 4A3S; 4I36; 
			
			

			» more