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PROSITE entry PS00382


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00382
Entry name [info] CLP_PROTEASE_HIS
Accession [info] PS00382
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED;
01-DEC-2001 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00358
Associated ProRule [info] PRU10086

Name and characterization of the entry

Description [info] Endopeptidase Clp histidine active site.
Pattern [info] 
R-x(3)-[EAP]-x(3)-[LIVMFYT]-[LM]-[LIVM]-H-Q-P.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 705 in 705 different sequences
Number of true positive hits 703 in 703 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 56
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 99.72 %
Recall (true positives / (true positives + false negatives)) 92.62 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 8
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 703 sequences 

CLPP1_AGRFC (Q8UEX6), CLPP1_ARATH (P56772), CLPP1_BACAN (Q81PL4),
» more

UniProtKB/Swiss-Prot
False negative sequences		 56 sequences 

CLPP1_BORBU (O51556), CLPP1_BRADU (Q89WR7), CLPP1_NOCFA (Q5Z0M4),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

CLPPH_POPEU (P84982), CLPP_PINST  (P84723)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			2 sequences
			


			
WDR11_HUMAN (Q9BZH6), WDR11_MOUSE (Q8K1X1)


				
	

	

		PDB
[Detailed view]		
		
			142 PDB
			


			1TG6; 1TYF; 1Y7O; 1YG6; 1YG8; 2C8T; 2CBY; 2CE3; 2FZS; 2ZL0; 2ZL2; 2ZL3; 
			
			

			» more