PROSITE entry PS00374
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PURL: https://purl.expasy.org/prosite/signature/PS00374
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General information about the entry
| Entry name [info] | MGMT |
| Accession [info] | PS00374 |
| Entry type [info] | PATTERN |
| Date [info] |
01-NOV-1990 CREATED;
01-NOV-1990 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00320 |
| Associated ProRule [info] | PRU10017 |
Name and characterization of the entry
| Description [info] | Methylated-DNA--protein-cysteine methyltransferase active site. |
| Pattern [info] |
[LIVMF]-P-C-H-R-[LIVMF](2). |
Numerical results [info]
| Total number of hits | 67 in 67 different sequences |
| Number of true positive hits | 53 in 53 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 14 in 14 different sequences |
| Number of false negative sequences | 2 |
| Number of 'partial' sequences | 1 |
| Precision (true positives / (true positives + false positives)) | 79.10 % |
| Recall (true positives / (true positives + false negatives)) | 96.36 % |
Comments [info]
| Taxonomic range [info] | Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Site [info] | active_site at position 3 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
53 sequences
ADAB_BACSU (P19220), ADA_ECOLI (P06134), ADA_SALTY (P26189),» more
|
| UniProtKB/Swiss-Prot False negative sequences |
2 sequences
ATL1_SCHPO (Q9UTN9), OGT_METKA (Q8TZ11) |
| UniProtKB/Swiss-Prot 'Partial' sequences |
1 sequence
MGMT_BOVIN (P29177) |
| UniProtKB/Swiss-Prot False positive sequences |
14 sequences
CFA65_HUMAN (Q6ZU64), KBTBC_HUMAN (Q3ZCT8), KBTBC_MOUSE (Q9D618),» more |
| PDB [Detailed view] |
26 PDB
1EH6; 1EH7; 1EH8; 1MGT; 1QNT; 1SFE; 1T39; 1WRJ; 1YFH; 2G7H; 4BHB; 4BHC; » more |