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PROSITE entry PS00373


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00373
Entry name [info] GART
Accession [info] PS00373
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00319

Name and characterization of the entry

Description [info] Phosphoribosylglycinamide formyltransferase active site.
Pattern [info] 
G-x-[STMC]-[IVTL]-x-[FYWVQELKR]-[VMAT]-x-[DEVMKAI]-x-[LIVMY]-D-x-G-x(2)-
[LIVTYA]-x(6)-[LIVM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 463 in 463 different sequences
Number of true positive hits 461 in 461 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 250
Number of 'partial' sequences 8
Precision (true positives / (true positives + false positives)) 99.57 %
Recall (true positives / (true positives + false negatives)) 64.84 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 12
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 461 sequences 

AL1L1_HUMAN (O75891), AL1L1_MOUSE (Q8R0Y6), AL1L1_PONAB (Q5RFM9),
» more

UniProtKB/Swiss-Prot
False negative sequences		 250 sequences 

FMT_ACIAD   (Q6F6P9), FMT_ACIB3   (B7GUZ7), FMT_ACIB5   (B7I2C3),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 8 sequences 

FMT_RICAK   (O33509), FMT_RICAM   (O33508), FMT_RICAU   (O33510),
» more

UniProtKB/Swiss-Prot
False positive sequences		 2 sequences 

ARNA_WIGBR  (Q8D341), ZNFX1_CAEEL (E9P860)


				
	

	

		PDB
[Detailed view]		
		
			59 PDB
			


			1C2T; 1C3E; 1CDD; 1CDE; 1FMT; 1GAR; 1GRC; 1JKX; 1MEJ; 1MEN; 1MEO; 1NJS; 
			
			

			» more