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PROSITE entry PS00354


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General information about the entry

Entry name [info] HMGI_Y
Accession [info] PS00354
Entry type [info] PATTERN
Date [info] 01-NOV-1990 CREATED;
01-OCT-1993 DATA UPDATE;
27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00306

Name and characterization of the entry

Description [info] HMG-I and HMG-Y DNA-binding domain (A+T-hook).
Pattern [info]
[AT]-x(1,2)-[RK](2)-[GP]-R-G-R-P-[RK]-x.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.


Total number of hits 39 in 27 different sequences
Number of true positive hits 32 in 20 different sequences
Number of 'unknown' hits 0
Number of false positive hits 7 in 7 different sequences
Number of false negative sequences 6
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 82.05 %
Recall (true positives / (true positives + false negatives)) 84.21 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
20 sequences

AFFL_DROER  (B3NAM7), AFFL_DROGR  (B4JQ42), AFFL_DROME  (Q9VQI9), 
AFFL_DROMO  (B4KFE1), AFFL_DROPS  (Q29KG4), AFFL_DROVI  (B4LV24), 
AFFL_DROWI  (B4MUE1), AFFL_DROYA  (B4NXA8), HMGA1_CANLF (Q6URC2), 
HMGA1_CRIGR (Q9QXP3), HMGA1_HUMAN (P17096), HMGA1_MOUSE (P17095), 
HMGA1_RAT   (Q8K585), HMGA2_HUMAN (P52926), KMT2C_HUMAN (Q8NEZ4), 
KMT2C_MOUSE (Q8BRH4), MYNN_DANRE  (Q7ZVR6), PATZ1_HUMAN (Q9HBE1), 
PATZ1_MOUSE (Q5NBY9), PRH_PETCR   (P48786)
» more

UniProtKB/Swiss-Prot
False negative sequences
6 sequences

AFFL_DROAN  (B3MLB7), CHIF_DROME  (Q9NK54), HMGA1_CHITE (Q23794), 
HMGA2_MOUSE (P52927), LI15B_CAEEL (Q27395), SFC3_SCHPO  (Q9UST7)
» more

UniProtKB/Swiss-Prot
False positive sequences
7 sequences

BRLF1_SHV21 (Q01012), CE087_XENLA (Q5XG50), HQ1_COXBU   (Q45881), 
KMT2A_HUMAN (Q03164), KMT2A_MOUSE (P55200), SLX4_PYRO7  (A4R1T1), 
WHIB7_MYCS2 (A0QTT1)
» more

PDB
[Detailed view]
2 PDB

2EZD; 2EZE