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PROSITE entry PS00236


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00236
Entry name [info] NEUROTR_ION_CHANNEL
Accession [info] PS00236
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00209

Name and characterization of the entry

Description [info] Neurotransmitter-gated ion-channels signature.
Pattern [info] 
C-x-[LIVMFQ]-x-[LIVMF]-x(2)-[FY]-P-x-D-x(3)-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 252 in 252 different sequences
Number of true positive hits 252 in 252 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 4
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 98.44 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Site [info] disulfide at position 1
Site [info] disulfide at position 12
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 252 sequences 

5HT3A_CAVPO (O70212), 5HT3A_HUMAN (P46098), 5HT3A_MOUSE (P23979),
» more

UniProtKB/Swiss-Prot
False negative sequences		 4 sequences 

5HT3B_HUMAN (O95264), 5HT3B_MOUSE (Q9JHJ5), 5HT3B_RAT   (Q9JJ16),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 5 sequences 

ACHA_ELEEL  (P09688), ACHB_CHICK  (P16005), ACHB_ELEEL  (P09689),
» more

PDB
[Detailed view]		 260 PDB

2BG9; 2QC1; 3JAD; 3JAE; 3JAF; 3RHW; 3RI5; 3RIA; 3RIF; 4AQ5; 4AQ9; 4BOG;
» more