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PROSITE entry PS00198


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00198
Entry name [info] 4FE4S_FER_1
Accession [info] PS00198
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00176

Name and characterization of the entry

Description [info] 4Fe-4S ferredoxin-type iron-sulfur binding region signature.
Pattern [info] 
C-x-{P}-C-{C}-x-C-{CP}-x-{C}-C-[PEG].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 2'632 in 1'465 different sequences
Number of true positive hits 2'588 in 1'436 different sequences
Number of 'unknown' hits 7 in 6 different sequences
Number of false positive hits 37 in 23 different sequences
Number of false negative sequences 46
Number of 'partial' sequences 4
Precision (true positives / (true positives + false positives)) 98.59 %
Recall (true positives / (true positives + false negatives)) 98.25 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 13
Site [info] iron_sulfur at position 1
Site [info] iron_sulfur at position 4
Site [info] iron_sulfur at position 7
Site [info] iron_sulfur at position 11
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 1436 sequences 

AB1E_ARATH  (Q9LID6), AB2E_ARATH  (Q8LPJ4), ABCE1_DROME (Q9VSS1),
» more

UniProtKB/Swiss-Prot
False negative sequences		 46 sequences 

ACDG1_METMA (Q8PZ09), ACDG1_METTE (Q50539), ACDG2_METMA (Q8PV87),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 4 sequences 

DSVB_MEGG1  (P94694), FERA_SULME  (P81543), FERB_SULME  (P81539),
» more

UniProtKB/Swiss-Prot
'Unknown' sequences		 6 sequences 

RPO3_ARCFU  (O28002), RPO3_METAC  (P0CG28), RPO3_METMA  (Q8PV16),
» more

UniProtKB/Swiss-Prot
False positive sequences		 23 sequences 

CADH7_ORYSJ (Q0JA75), CHHA2_BOMMO (P05687), CHHB2_BOMMO (P20730),
» more

PDB
[Detailed view]		 517 PDB

1A6L; 1AXQ; 1B0P; 1B0T; 1B0V; 1BC6; 1BD6; 1BLU; 1BQX; 1BWE; 1C4A; 1C4C;
» more