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PROSITE entry PS00197


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00197
Entry name [info] 2FE2S_FER_1
Accession [info] PS00197
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-1991 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00175

Name and characterization of the entry

Description [info] 2Fe-2S ferredoxin-type iron-sulfur binding region signature.
Pattern [info] 
C-{C}-{C}-[GA]-{C}-C-[GAST]-{CPDEKRHFYW}-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 363 in 358 different sequences
Number of true positive hits 298 in 297 different sequences
Number of 'unknown' hits 1
Number of false positive hits 64 in 60 different sequences
Number of false negative sequences 123
Number of 'partial' sequences 12
Precision (true positives / (true positives + false positives)) 82.32 %
Recall (true positives / (true positives + false negatives)) 70.78 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] iron_sulfur at position 1
Site [info] iron_sulfur at position 6
Site [info] iron_sulfur at position 9
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 297 sequences 

ALDO1_ARATH (Q7G193), ALDO1_MAIZE (O23887), ALDO1_ORYSJ (Q7XH05),
» more

UniProtKB/Swiss-Prot
False negative sequences		 123 sequences 

CSMI_CHLTE  (O68988), CSMJ_CHLTE  (O68983), CUTC_SULAC  (Q4J6M5),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 12 sequences 

FER2_PEA(Q7M258), FER_ANASL   (P83156), FER_PORAE   (P18820),
» more

UniProtKB/Swiss-Prot
'Unknown' sequences		 1 sequence 

RNFB_METAC  (Q8TSX9)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			60 sequences
			


			
105R_ADES1  (A9CBA2), ANCHR_HUMAN (Q96K21), BRL1_SCHPO  (Q1MTQ0), 

			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			205 PDB
			


			1A70; 1AWD; 1CZP; 1DOI; 1DOX; 1DOY; 1E0Z; 1E10; 1E7P; 1EWY; 1FIQ; 1FO4; 
			
			

			» more