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PROSITE entry PS00183


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00183
Entry name [info] UBC_1
Accession [info] PS00183
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00163
Associated ProRule [info] PRU10133

Name and characterization of the entry

Description [info] Ubiquitin-conjugating (UBC) active site signature.
Pattern [info] 
[FYWLSP]-H-[PC]-[NHL]-[LIV]-x(3,4)-G-x-[LIVP]-C-[LIV]-x(1,2)-[LIVR].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 242 in 242 different sequences
Number of true positive hits 242 in 242 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 81
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 74.92 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] active_site at position 10
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 242 sequences 

PEX4_ARATH  (Q8LGF7), PEX4_KOMPG  (C4R826), PEX4_PICPA  (P49428),
» more

UniProtKB/Swiss-Prot
False negative sequences		 81 sequences 

BIRC6_HUMAN (Q9NR09), BIRC6_MOUSE (O88738), COP10_ARATH (Q9LJD7),
» more

PDB
[Detailed view]		 299 PDB

1A3S; 1AYZ; 1C4Z; 1FBV; 1FXT; 1FZY; 1J7D; 1JAS; 1JAT; 1JBB; 1KPS; 1PZV;
» more