PROSITE entry PS00178

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PURL: https://purl.expasy.org/prosite/signature/PS00178

Direct ScanProsite submission

General information about the entry

Entry name [info]	AA_TRNA_LIGASE_I
Accession [info]	PS00178
Entry type [info]	PATTERN
Date [info]	01-APR-1990 CREATED; 01-NOV-1997 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00161

Name and characterization of the entry

Description [info]	Aminoacyl-transfer RNA synthetases class-I signature.
Pattern [info]	P-x(0,2)-[GSTAN]-[DENQGAPK]-x-[LIVMFP]-[HT]-[LIVMYAC]-G-[HNTG]- [LIVMFYSTAGPC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_04 which contains 573'661 sequence entries.

Total number of hits	4'405 in 4'402 different sequences
Number of true positive hits	4'055 in 4'055 different sequences
Number of 'unknown' hits	0
Number of false positive hits	350 in 347 different sequences
Number of false negative sequences	1'536
Number of 'partial' sequences	8

Precision (true positives / (true positives + false positives))	92.05 %
Recall (true positives / (true positives + false negatives))	72.53 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info]	3
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	4055 sequences FUBP2_MOUSE (Q3U0V1), GLUQ_BIFLO (Q8G4X3), GLUQ_DEIGD (Q1IZL1), » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	1536 sequences CPS11_ORYSJ (Q0IZQ2), CPS1_MAIZE (A0A1D6LAG9), GLUQ_ACIAD (Q6FFC0), » more
UniProtKB/Swiss-Prot 'Partial' sequences	8 sequences SY1_PHYPO (P84178), SYE_STAXY (P77984), SYIM_CIOIN (Q94425), » more
UniProtKB/Swiss-Prot False positive sequences	347 sequences ACE1_PYRO7 (G4MVZ2), ACFD_ECOH1 (E3PJ90), ACFD_ECOLI (P0CK95), » more
PDB [Detailed view]	309 PDB pdb_00001bs2; pdb_00001d2r; pdb_00001euq; pdb_00001euy; pdb_00001exd; pdb_00001f4l; pdb_00001f7u; pdb_00001f7v; pdb_00001ffy; pdb_00001g59; pdb_00001gax; pdb_00001gln; » more