PROSITE entry PS00177
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PURL: https://purl.expasy.org/prosite/signature/PS00177
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General information about the entry
| Entry name [info] | TOPOISOMERASE_II |
| Accession [info] | PS00177 |
| Entry type [info] | PATTERN |
| Date [info] |
01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00160 |
Name and characterization of the entry
| Description [info] | DNA topoisomerase II signature. |
| Pattern [info] |
[LIVMA]-{R}-E-G-[DN]-S-A-{F}-[STAG].
|
Numerical results [info]
| Total number of hits | 185 in 185 different sequences |
| Number of true positive hits | 170 in 170 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 15 in 15 different sequences |
| Number of false negative sequences | 3 |
| Number of 'partial' sequences | 2 |
| Precision (true positives / (true positives + false positives)) | 91.89 % |
| Recall (true positives / (true positives + false negatives)) | 98.27 % |
Comments [info]
| Taxonomic range [info] | Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
170 sequences
CIN4_CAEEL (G5ECQ8), GYRB1_ACILW (Q44088), GYRB2_ACILW (Q44272),» more
|
| UniProtKB/Swiss-Prot False negative sequences |
3 sequences
GYRB_ARCFU (O29720), TOP2_CANAX (P87078), TOP2_PICGU (Q01879) |
| UniProtKB/Swiss-Prot 'Partial' sequences |
2 sequences
GYRB_PROMI (P22840), GYRB_RHOCA (P31860) |
| UniProtKB/Swiss-Prot False positive sequences |
15 sequences
ASTD_PARXL (Q141D3), CIPK6_ORYSJ (Q6Z9F4), DARP_XYLFA (Q9PE98),» more |
| PDB [Detailed view] |
124 PDB
1BGW; 1BJT; 2RGR; 2XCO; 2XCQ; 2XCR; 2XCS; 2XCT; 2ZJT; 3FOE; 3FOF; 3IG0; » more |