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PROSITE entry PS00171


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PURL: https://purl.expasy.org/prosite/signature/PS00171

Direct ScanProsite submission
General information about the entry

Entry name [info] TIM_1
Accession [info] PS00171
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00155
Associated ProRule [info] PRU10127

Name and characterization of the entry

Description [info] Triosephosphate isomerase active site.
Pattern [info] 
[AVG]-[YLV]-E-P-[LIVMEPKST]-[WYEAS]-[SAL]-[IV]-[GN]-[TEKDVS]-[GKNAD].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 640 in 640 different sequences
Number of true positive hits 640 in 640 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 20
Number of 'partial' sequences 4
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 96.97 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 640 sequences 

ERYH_BRUA2  (Q2YIQ6), ERYH_BRUAB  (P0C119), ERYH_BRUME  (Q8YCV3),
» more

UniProtKB/Swiss-Prot
False negative sequences		 20 sequences 

LERI_PECAS  (Q6D8V5), TPIS_BARBK  (A1US90), TPIS_BAUCH  (Q1LTT4),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 4 sequences 

TPIS_CLOPA  (P81348), TPIS_MYCPI  (P47721), TPIS_NICPL  (P19118),
» more

PDB
[Detailed view]		 198 PDB

1AG1; 1AMK; 1AW1; 1AW2; 1B9B; 1BTM; 1CI1; 1DKW; 1HG3; 1HTI; 1I45; 1IF2;
» more