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PROSITE entry PS00165


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00165
Entry name [info] DEHYDRATASE_SER_THR
Accession [info] PS00165
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00149

Name and characterization of the entry

Description [info] Serine/threonine dehydratases pyridoxal-phosphate attachment site.
Pattern [info] 
[DESH]-x(4,5)-[STVG]-{EVKD}-[AS]-[FYI]-K-[DLIFSA]-[RLVMF]-[GA]-[LIVMGA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 226 in 226 different sequences
Number of true positive hits 193 in 193 different sequences
Number of 'unknown' hits 0
Number of false positive hits 33 in 33 different sequences
Number of false negative sequences 19
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 85.40 %
Recall (true positives / (true positives + false negatives)) 91.04 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] pyridoxal_phosphate at position 7
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 193 sequences 

AKS11_ALTAL (V5Y0V0), ILVA_BACSU  (P37946), ILVA_BURM1  (P53607),
» more

UniProtKB/Swiss-Prot
False negative sequences		 19 sequences 

SDHD_ACIET  (B9MIR7), SDHD_ACISJ  (A1W838), SDHD_BURL3  (Q396Y3),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

TD_SOLTU(P31212)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			33 sequences
			


			
ACTN3_BOVIN (Q0III9), ACTN3_HUMAN (Q08043), ACTN3_MOUSE (O88990), 

			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			36 PDB
			


			1E5X; 1KL7; 1P5J; 1PWE; 1PWH; 1TDJ; 1VB3; 2C2B; 2C2G; 2D1F; 2GN0; 2GN1; 
			
			

			» more