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PROSITE entry PS00144


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PURL: https://purl.expasy.org/prosite/signature/PS00144

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General information about the entry

Entry name [info] ASN_GLN_ASE_1
Accession [info] PS00144
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00132
Associated ProRule [info] PRU10099

Name and characterization of the entry

Description [info] Asparaginase / glutaminase active site signature 1.
Pattern [info]
[LIVM]-x-{L}-T-G-G-T-[IV]-[AGS].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 129 in 129 different sequences
Number of true positive hits 53 in 53 different sequences
Number of 'unknown' hits 1
Number of false positive hits 75 in 75 different sequences
Number of false negative sequences 18
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 41.41 %
Recall (true positives / (true positives + false negatives)) 74.65 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 7
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
53 sequences

ASP21_YEAST (P0CZ17), ASP22_YEAST (P0CX77), ASP23_YEAST (P0CX78), 
» more

UniProtKB/Swiss-Prot
False negative sequences
18 sequences

ASPG_PYRFU  (Q8TZE8), GATD_AERPE  (Q9Y9T8), GATD_METS5  (A4YHH3), 
» more

UniProtKB/Swiss-Prot
'Unknown' sequences
1 sequence

DESPA_DANRE (A0A8M2BID5)

		
UniProtKB/Swiss-Prot
False positive sequences
75 sequences

API10_SOLTU (Q03197), API11_SOLTU (P16348), API1_SOLTU  (Q41480), 
» more

PDB
[Detailed view]
86 PDB

1AGX; 1DJO; 1DJP; 1HFJ; 1HFK; 1HFW; 1HG0; 1HG1; 1HO3; 1IHD; 1JAZ; 1JJA;
» more