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PROSITE entry PS00138


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PURL: https://purl.expasy.org/prosite/signature/PS00138

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General information about the entry

Entry name [info] SUBTILASE_SER
Accession [info] PS00138
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00125
Associated ProRule [info] PRU10082

Name and characterization of the entry

Description [info] Serine proteases, subtilase family, serine active site.
Pattern [info] 
G-T-S-x-[SA]-x-P-x-{L}-[STAVC]-[AG].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 356 in 353 different sequences
Number of true positive hits 323 in 323 different sequences
Number of 'unknown' hits 0
Number of false positive hits 33 in 30 different sequences
Number of false negative sequences 6
Number of 'partial' sequences 7
Precision (true positives / (true positives + false positives)) 90.73 %
Recall (true positives / (true positives + false negatives)) 98.18 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 4
Site [info] active_site at position 3
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 323 sequences 

AEP_YARLI   (P09230), AIR3_ARATH  (Q9ZSP5), ALP2_ASPFC  (B0Y473),
» more

UniProtKB/Swiss-Prot
False negative sequences		 6 sequences 

SBT1_LOTJA  (A9QY40), SBT3_LOTJA  (A9QY39), SBT4_LOTJA  (A9QY38),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 7 sequences 

ASE2_ACRSP  (P85157), CUDP_METCM  (P80406), NCP3_COPCM  (P83454),
» more

UniProtKB/Swiss-Prot
False positive sequences		 30 sequences 

DCA11_CAEEL (P90794), FOSB_CANLF  (Q9TUB3), FOSB_HUMAN  (P53539),
» more

PDB
[Detailed view]		 424 PDB

1A2Q; 1AF4; 1AH2; 1AK9; 1AQN; 1AU9; 1AV7; 1BE6; 1BE8; 1BFK; 1BFU; 1BH6;
» more