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PROSITE entry PS00132


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PURL: https://purl.expasy.org/prosite/signature/PS00132

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General information about the entry

Entry name [info] CARBOXYPEPT_ZN_1
Accession [info] PS00132
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00123

Name and characterization of the entry

Description [info] Zinc carboxypeptidases, zinc-binding region 1 signature.
Pattern [info]
[PK]-x-[LIVMFY]-x-[LIVMFY]-x(2)-{E}-x-H-[STAG]-x-E-x-[LIVM]-[STAG]-{L}-
x(5)-[LIVMFYTA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 106 in 101 different sequences
Number of true positive hits 99 in 94 different sequences
Number of 'unknown' hits 0
Number of false positive hits 7 in 7 different sequences
Number of false negative sequences 55
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 93.40 %
Recall (true positives / (true positives + false negatives)) 64.29 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Site [info] zinc at position 9
Site [info] zinc at position 12
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
94 sequences

AEBP1_HUMAN (Q8IUX7), AEBP1_MOUSE (Q640N1), AEBP1_RAT   (A2RUV9), 
» more

UniProtKB/Swiss-Prot
False negative sequences
55 sequences

CBPA3_HUMAN (P15088), CBPA6_HUMAN (Q8N4T0), CBPA6_MOUSE (Q5U901), 
» more

UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

CBP1_SABMA  (P86516), CBPB_PROAT  (P19628)

		
UniProtKB/Swiss-Prot
False positive sequences
7 sequences

AUSK_EMENI  (C8VQ93), AUSK_PENBI  (A0A0F7TN16), BGLL_ASPTN  (Q0CEF3), 
» more

PDB
[Detailed view]
119 PDB

1ARL; 1ARM; 1AYE; 1BAV; 1CBX; 1CPB; 1CPS; 1CPX; 1DTD; 1EE3; 1ELL; 1ELM;
» more