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PROSITE entry PS00124


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PURL: https://purl.expasy.org/prosite/signature/PS00124

Direct ScanProsite submission
General information about the entry

Entry name [info] FBPASE
Accession [info] PS00124
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2001 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00114
Associated ProRule [info] PRU10043

Name and characterization of the entry

Description [info] Fructose-1-6-bisphosphatase active site.
Pattern [info] 
[AG]-[RK]-[LI]-x(1,2)-[LIV]-[FY]-E-x(2)-P-[LIVM]-[GSA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 225 in 225 different sequences
Number of true positive hits 222 in 222 different sequences
Number of 'unknown' hits 0
Number of false positive hits 3 in 3 different sequences
Number of false negative sequences 182
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 98.67 %
Recall (true positives / (true positives + false negatives)) 54.95 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 2
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 222 sequences 

F16A1_ACAM1 (B0CAD9), F16A1_ALBFT (Q21YM7), F16A1_BRASB (A5E987),
» more

UniProtKB/Swiss-Prot
False negative sequences		 182 sequences 

F16A1_CUPMC (Q1LQ15), F16A1_CUPNH (Q0KCY0), F16A1_CUPTR (B3R3R6),
» more

UniProtKB/Swiss-Prot
False positive sequences		 3 sequences 

WDR81_HUMAN (Q562E7), WDR81_MOUSE (Q5ND34), WDR81_RAT   (D4A929)


				
	

	

		PDB
[Detailed view]		
		
			142 PDB
			


			1BK4; 1CNQ; 1D9Q; 1DBZ; 1DCU; 1EYI; 1EYJ; 1EYK; 1FBC; 1FBD; 1FBE; 1FBF; 
			
			

			» more