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PROSITE entry PS00123


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PURL: https://purl.expasy.org/prosite/signature/PS00123

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General information about the entry

Entry name [info] ALKALINE_PHOSPHATASE
Accession [info] PS00123
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-OCT-1993 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00113
Associated ProRule [info] PRU10042

Name and characterization of the entry

Description [info] Alkaline phosphatase active site.
Pattern [info]
[IV]-x-D-S-[GAS]-[GASC]-[GAST]-[GA]-T.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 36 in 36 different sequences
Number of true positive hits 27 in 27 different sequences
Number of 'unknown' hits 0
Number of false positive hits 9 in 9 different sequences
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 75.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 4
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
27 sequences

APH4_DROME  (Q24238), PPB1_HUMAN  (P05187), PPB3_BACSU  (P19405), 
» more

UniProtKB/Swiss-Prot
False positive sequences
9 sequences

CIAO1_ASPCL (A1CQL6), FBID2_RHOJR (Q0RVJ9), INF2_HUMAN  (Q27J81), 
» more

PDB
[Detailed view]
54 PDB

1AJA; 1AJB; 1AJC; 1AJD; 1ALH; 1ALI; 1ALJ; 1ALK; 1ANI; 1ANJ; 1B8J; 1ED8;
» more