PROSITE entry PS00122
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PURL: https://purl.expasy.org/prosite/signature/PS00122
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General information about the entry
| Entry name [info] | CARBOXYLESTERASE_B_1 |
| Accession [info] | PS00122 |
| Entry type [info] | PATTERN |
| Date [info] |
01-APR-1990 CREATED;
01-NOV-1995 DATA UPDATE; 29-MAY-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC00112 |
| Associated ProRule [info] | PRU10039 |
Name and characterization of the entry
| Description [info] | Carboxylesterases type-B serine active site. |
| Pattern [info] |
F-[GR]-G-x(4)-[LIVM]-x-[LIV]-x-G-x-S-[STAG]-G. |
Numerical results [info]
| Total number of hits | 133 in 133 different sequences |
| Number of true positive hits | 131 in 131 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 2 in 2 different sequences |
| Number of false negative sequences | 4 |
| Number of 'partial' sequences | 14 |
| Precision (true positives / (true positives + false positives)) | 98.50 % |
| Recall (true positives / (true positives + false negatives)) | 97.04 % |
Comments [info]
| Taxonomic range [info] | Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses |
| Maximum number of repetitions [info] | 1 |
| Site [info] | active_site at position 11 |
| Version [info] | 1 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
131 sequences
ACE1_CAEBR (Q27459), ACE1_CAEEL (P38433), ACE4_CAEBR (Q9NDG8),» more
|
| UniProtKB/Swiss-Prot False negative sequences |
4 sequences
ACES_TRILK (W4VSJ0), CES1P_HUMAN (Q9UKY3), ESTE_HVAVE (A4KX74),» more |
| UniProtKB/Swiss-Prot 'Partial' sequences |
14 sequences
ACES_CULPP (Q867X3), ACES_CULQU (Q867X2), ACES_CULTO (Q86GC9),» more |
| UniProtKB/Swiss-Prot False positive sequences |
2 sequences
ICME_ARATH (Q94AS5), ICML2_ARATH (Q1PET6) |
| PDB [Detailed view] |
434 PDB
1ACJ; 1ACL; 1AKN; 1AMN; 1AQL; 1AX9; 1B41; 1C2B; 1C2O; 1C7I; 1C7J; 1CFJ; » more |