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| Entry: PS00118 |
| General information about the entry | |
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| Entry name | PA2_HIS |
| Accession number | PS00118 |
| Entry type | PATTERN |
| Date | APR-1990 (CREATED); DEC-2004 (DATA UPDATE); JUL-2010 (INFO UPDATE). |
| PROSITE Documentation | PDOC00109 |
| Associated ProRule | PRU10035 |
| Name and characterization of the entry | |
| Description | Phospholipase A2 histidine active site. |
| Pattern | C-C-{P}-x-H-{LGY}-x-C. |
| Numerical results | |
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| Comments | |
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| Cross-references | |
| UniProtKB/Swiss-Prot | True positive hits:CYSP1_ORYSJ (Q7XR52), IPTXI_PANIM (P59888), NADK3_ORYSJ (Q60E60), OC90_HUMAN (Q02509), OC90_MOUSE (Q9Z0L3), PA20_BUNMU (P00606), PA20_LAPHA (Q8UW08), PA20_NOTSC (P08873), PA20_PSEAU (P20254), PA210_AUSSU (Q9PUH4), PA211_AUSSU (Q9PUH3), PA212_AUSSU (Q9PUH2), PA212_CRODR (P0CAS3), PA213_AUSSU (Q9PUH1), PA213_CRODR (P0CAS4), PA214_AUSSU (Q9PUH0), PA215_AUSSU (Q9PUG9), PA215_CRODU (P0CAS5), PA216_CRODU (P0CAS6), PA217_AUSSU (Q9PUG7), PA217_CRODU (P0CAS7), PA21B_ACAAN (P81236), PA21B_AGKHA (P04417), PA21B_AGKHP (P14418), PA21B_AUSSU (P59359), PA21B_BOTJA (P81243), PA21B_BOTMO (P82114), PA21B_BOTPI (P58399), PA21B_BOVIN (P00593), PA21B_BUNCE (Q8QFW4), PA21B_BUNFA (Q90WA7), PA21B_BUNMU (P00617), PA21B_CANFA (P06596), PA21B_CAVPO (P43434), PA21B_ERIMA (P24293), PA21B_HORSE (P00594), PA21B_HUMAN (P04054), PA21B_LATLA (P19000), PA21B_LATSE (P00611), PA21B_MOUSE (Q9Z0Y2), PA21B_NAJME (P00599), PA21B_NAJMO (P00602), PA21B_NAJOX (P25498), PA21B_NAJSG (P60043), PA21B_NOTSC (P00607), PA21B_OPHHA (P80966), PA21B_OXYSC (P00614), PA21B_PIG (P00592), PA21B_PSEAU (P04056), PA21B_PSETE (Q9W7J4), PA21B_RABIT (Q7M334), PA21B_RAT (P04055), PA21B_SHEEP (P14419), PA21B_TRIFL (P06859), PA21B_TRIGA (P20476), PA21B_TRIMU (Q91506), PA21B_TRIOK (P00625), PA21B_VIPAE (P14420), PA21B_VIPAP (Q8JFG0), PA21P_VIPNI (Q1RP79), PA21_ACAPL (Q3C2C2), PA21_AGKPI (P51972), PA21_BOTAS (P20474), PA21_BOTIN (Q8QG87), PA21_BOTMO (P0C8M1), PA21_BUNCA (Q75S48), PA21_BUNFL (Q7T2Q5), PA21_CERCE (P0CAR9), PA21_ECHCO (Q90ZZ9), PA21_HEMHA (P00595), PA21_LACMU (P0C932), PA21_NAJAT (P00598), PA21_NAJKA (P00596), PA21_TROCA (Q45Z30), PA22P_VIPNI (Q1RP78), PA22_ACAAN (P81237), PA22_ACAPL (Q3C2C1), PA22_AGKHA (P20249), PA22_ASPSC (P07037), PA22_AUSSU (Q9PUI1), PA22_BITNA (P00621), PA22_BOTAS (P86389), PA22_BOTIN (P84397), PA22_BOTMO (Q9I834), PA22_BOTPI (P82287), PA22_BUNCE (Q8QFW3), PA22_BUNFA (Q90WA8), PA22_BUNFL (Q7T2Q4), PA22_BUNMU (P00618), PA22_CERCE (P0CAS0), PA22_CERGO (P81165), PA22_ERIMA (P24294), PA22_HELSU (P80003), PA22_LACMU (P0C933), PA22_LATCO (P10116), PA22_LATLA (Q8UUI4), PA22_NAJAT (Q91133), PA22_NAJKA (P00597), PA22_NAJME (P00600), PA22_NAJMO (P00603), PA22_NAJSG (P60044), PA22_NOTSC (P00608), PA22_OPHHA (Q9DF33), PA22_OXYSC (P00615), PA22_PIG (P04416), PA22_PSETE (Q9W7J3), PA22_TRIGA (P81478), PA22_TRIMU (Q9I968), PA22_TROCA (Q45Z29), PA22_VIPAZ (Q10755), PA23_AGKHP (P14421), PA23_AUSSU (Q9PRG0), PA23_BOTPI (P58464), PA23_BUNMU (P00619), PA23_DABRR (P86368), PA23_ECHCO (Q910A0), PA23_HELSU (P16354), PA23_LATCO (Q8UUI0), PA23_LATLA (Q8UUI3), PA23_LATSE (P00612), PA23_NAJME (P00601), PA23_NAJMO (P00604), PA23_NAJNG (P00605), PA23_NAJSG (P60045), PA23_NOTSC (P00609), PA23_OPHHA (Q9DF56), PA23_OXYSC (P00616), PA23_PSEAU (P20251), PA23_TRIGA (P81480), PA23_TRIOK (Q92152), PA23_TROCA (Q45Z28), PA24_AGKHP (O42187), PA24_AUSSU (Q9PUI0), PA24_BUNMU (P17934), PA24_DABRU (Q02471), PA24_ECHCS (P59170), PA24_LATCO (Q8UUH9), PA24_LATLA (Q8UUI2), PA24_LATSE (P00613), PA24_NAJSG (Q6T179), PA24_TRIGA (P81479), PA24_TROCA (Q45Z27), PA25_AGKHP (O42189), PA25_AUSSU (Q9PUH9), PA25_BUNMU (P59018), PA25_DABRR (P84674), PA25_ECHOC (P59171), PA25_ECHPL (P59172), PA25_LAPHA (Q8UW31), PA25_LATCO (Q8UUH8), PA25_LATLA (Q8UUI1), PA25_NAJSG (Q5G291), PA25_PSEAU (P20252), PA25_TRIGA (P70090), PA25_TRIST (P82896), PA25_TROCA (Q45Z26), PA26A_CRODO (P0CAS2), PA26_AGKHP (O42190), PA26_AUSSU (Q9PUH8), PA26_BUNFA (P00627), PA26_BUNMU (Q90251), PA26_LATCO (Q8UUH7), PA26_NAJSG (Q5G290), PA26_TRIGA (P70088), PA26_TROCA (Q45Z25), PA27_AGKHP (O42191), PA27_AUSSU (Q9PUH7), PA27_BOTNE (Q9IAT9), PA27_BUNMU (Q9PU97), PA27_DABRU (P31100), PA27_LAPHA (Q8UW30), PA27_TRIGA (P70089), PA27_VIPPA (Q9PWR6), PA28_AGKHP (O42192), PA28_AUSSU (Q9PUH6), PA28_DABRR (P59071), PA28_VIPPA (Q9YGJ7), PA29_AGKHP (O42188), PA29_AUSSU (Q9PUH5), PA29_PSEAU (P20253), PA2A1_BUNCA (Q8AY48), PA2A1_BUNFL (Q7T1R0), PA2A2_BUNCA (Q8AY47), PA2A2_BUNFL (Q7T1R1), PA2A3_BUNCA (Q6YNQ0), PA2A4_BUNCA (Q75S51), PA2A_AGKAC (Q7SID6), PA2A_AGKRH (Q9PVF1), PA2A_BUNCA (Q6YIJ3), PA2A_BUNFA (P00628), PA2A_CRODR (P86169), PA2A_CRODU (P08878), PA2A_CROSS (P18998), PA2A_GLOUS (Q7LZQ4), PA2A_LATSE (Q9I847), PA2A_MICNI (P81166), PA2A_NAJSP (Q92084), PA2A_PSEAU (P20255), PA2A_PSEPO (P20258), PA2A_PSETE (P23026), PA2A_TRIFL (P59264), PA2A_TRIMU (Q90W39), PA2A_VIPAA (P00626), PA2A_VIPPA (Q98996), PA2B1_BOTJR (Q90249), PA2B2_BOTJR (P45881), PA2B2_TRIST (P82893), PA2B_AGKAC (Q1ZY03), PA2B_AGKRH (Q9PVF0), PA2B_BUNCA (Q802I1), PA2B_BUNFA (P00629), PA2B_BUNMU (Q9PTA7), PA2B_CRODU (P62022), PA2B_CROSS (P62023), PA2B_LATSE (Q9I846), PA2B_MICNI (P81167), PA2B_NAJSP (Q92085), PA2B_PSEPO (P20259), PA2B_PSETE (P23027), PA2B_TRIFL (P59265), PA2B_TRIMU (P22640), PA2B_VIPAA (P14424), PA2C_AGKRH (Q9PVE9), PA2C_BUNMU (Q9PTA6), PA2C_CRODU (P24027), PA2C_LATSE (Q9I845), PA2C_NAJSP (Q92086), PA2C_PSEAU (P20256), PA2C_PSETE (P30811), PA2C_VIPAA (P11407), PA2D_AGKRH (Q9PVF4), PA2D_BUNMU (Q9PTA5), PA2D_LATSE (Q9I844), PA2D_NAJSP (Q9I900), PA2D_PSEAU (P04057), PA2D_PSETE (P23028), PA2E_AGKRH (Q9PVF2), PA2E_LATSE (Q9I843), PA2E_NOTSC (Q9PSN5), PA2E_PSEAU (P20257), PA2F_AGKRH (Q9PVF3), PA2F_LATSE (Q9I842), PA2G3_BOVIN (Q1JPB9), PA2G3_HUMAN (Q9NZ20), PA2G5_HUMAN (P39877), PA2G5_MOUSE (P97391), PA2G5_RAT (P51433), PA2GA_BOVIN (Q56JZ2), PA2GA_CAVPO (P47711), PA2GA_HUMAN (P14555), PA2GA_MOUSE (P31482), PA2GA_RAT (P14423), PA2GC_MOUSE (P48076), PA2GC_RAT (P39878), PA2GD_HUMAN (Q9UNK4), PA2GD_MOUSE (Q9WVF6), PA2GE_HUMAN (Q9NZK7), PA2GE_MOUSE (Q9QUL3), PA2GF_HUMAN (Q9BZM2), PA2GF_MOUSE (Q9QZT4), PA2GX_HUMAN (O15496), PA2GX_MOUSE (Q9QXX3), PA2GX_RAT (Q9QZT3), PA2G_BUNFA (P0C551), PA2G_LATSE (Q9I837), PA2G_PSEAU (P20250), PA2H1_BOTAT (Q6JK69), PA2H2_BOTAS (P24605), PA2H3_BOTAS (Q9PVE3), PA2HA_BOTAS (P0C616), PA2H_AGKAC (O57385), PA2H_AGKPI (P04361), PA2H_ATRNM (P82950), PA2H_BOTSC (P80963), PA2H_BUNFA (P29601), PA2H_CERGO (Q8UVU7), PA2H_CROAT (Q8UVZ7), PA2H_LATSE (Q8JFG2), PA2H_ZHAMA (P84776), PA2I_LATSE (Q8JFB2), PA2J_TRIFL (P20381), PA2K_BUNCE (Q9DF52), PA2L_CAEEL (Q9U256), PA2L_VIPAA (P17935), PA2M_AGKCL (P49121), PA2N_BUNFA (P14615), PA2N_ECHCA (P48650), PA2N_NAJAT (A4FS04), PA2N_TRIFL (Q805A2), PA2N_VIPAA (P34180), PA2P_TRIFL (Q92147), PA2Q_TRIFL (Q8JIG0), PA2R4_BOTAL (P86456), PA2S_AUSSU (P59067), PA2T1_LACMU (P0C942), PA2T2_LACMU (P0C943), PA2TX_BOTAL (P86453), PA2T_AUSSU (P59068), PA2W_TRIFL (Q02517), PA2X_BUNFA (P14411), PA2X_NOTSC (P20146), PA2X_TRIFL (P06860), PA2Y_TRIFL (Q90Y77), PA2_ADAPA (Q8WS88), PA2_AIPLA (P08872), PA2_APICC (Q9BMK4), PA2_APIDO (Q7M4I5), PA2_APIME (P00630), PA2_BITCA (P00622), PA2_BITGA (P00620), PA2_BOMTE (P82971), PA2_BOTPC (Q9I8F8), PA2_CERCE (P21789), PA2_CROAD (P00623), PA2_CROAT (P00624), PA2_DABRR (P81458), PA2_ENHSC (P00610), PA2_HADGE (P0C8L9), PA2_HELHO (P04362), PA2_LACST (P84651), PA2_MEGPE (Q7M4I6), PA2_NAJNA (P15445), PA2_NAJPA (P14556), PA2_TRIJE (Q8JIY9), PA2_VIPAA (Q910A1), PA2_VIPBB (P31854), PG12A_HUMAN (Q9BZM1), PG12A_MOUSE (Q9EPR2), PHLIP_ANUPH (Q6PXP0), PLA21_ORYSJ (Q9XG80), PLA22_ORYSJ (Q9XG81), PLA23_ORYSJ (Q10E50)False negative hits (sequences which belong to the set under consideration, but which have not been picked up by the pattern or profile): PA216_AUSSU (Q9PUG8), PA21B_VIPAZ (Q10754), PA21I_VIPNI (A4VBF0), PA2A_BUNMU (Q9PTA1), PA2GC_HUMAN (Q5R387), PA2H_LATCO (P10117), PA2H_XENLA (P41485), PA2I_VIPAE (P04084), PA2I_VIPAP (Q8JFG1), PG12B_HUMAN (Q9BX93), PG12B_MOUSE (Q99P27)`Potential' hits (partial sequences which belong to the set under consideration, but which are not hit by the pattern or profile because they are partial (fragment) sequences): OC90_CAVPO (P81869), PA21A_BUNCA (P84475), PA21B_MATBI (P24644), PA21B_MICFM (P25072), PA21B_MICNI (P21790), PA21B_STRCA (P86043), PA21_DABRR (P86529), PA22A_BUNCA (P84472), PA22_AGKHP (P18997), PA22_MATBI (P24645), PA22_MICNI (P21791), PA22_OPICY (P86120), PA23_MICNI (P21792), PA23_NAJNA (P86542), PA23_TRIST (P82894), PA24_BOTJR (P0CAR8), PA24_TRIST (P82895), PA26_CRODM (P0CAS1), PA2A1_ACASE (P85062), PA2A1_MICPY (P0CAS8), PA2A2_ACASS (P85060), PA2A3_ACASS (P85061), PA2AA_ACAAN (P86523), PA2AB_ACAAN (P86524), PA2AC_ACAAN (P86525), PA2B1_MICPY (P0CAS9), PA2B1_TRIST (P82892), PA2B_VIPBO (P31859), PA2C_PSEPO (P20260), PA2D5_MICPY (P0CAT0), PA2D6_MICPY (P0CAT1), PA2GA_RABIT (P14422), PA2T2_BUNCA (P84474), PA2U_AUSSU (P59069), PA2V_AUSSU (P59070), PA2_AGKBI (Q9PSF9), PA2_CARAE (P86517), PA2_DABRU (P18999), PA2_NAJSP (Q10756), PA2_RHONO (P43318), PA2_TRIBL (P84736)False positive hits (sequences which do not belong to the set under consideration): BH055_ARATH (Q9LN95), CC129_HUMAN (Q6ZRS4), CTDA_CONTE (Q9BPH1), GRN_CAVPO (P28797), GRN_HUMAN (P28799), GRN_MOUSE (P28798), GRN_RAT (P23785), HMHA1_XENLA (Q6DE55), INSC_HUMAN (Q1MX18), IPO4_HUMAN (Q8TEX9), KCNN_DROME (Q7KVW5), LCE3A_HUMAN (Q5TA76), LCE3B_HUMAN (Q5TA77), MLT7_CAEEL (Q23490), NALP3_BOVIN (A6QLE5), ORYB_ORYSJ (P25777), PATE1_HUMAN (Q8WXA2), PRCA1_HUMAN (Q8NCQ7), PRCA1_RAT (Q4V7B4), PROM2_HUMAN (Q8N271), TM7S4_HUMAN (Q9H295)Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view]
[Clustal format, color]
[Clustal format, plain text]
[Fasta format]
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| PDB [Detailed view] | 1A2A; 1A3D; 1A3F; 1AE7; 1AOK; 1AYP; 1B4W; 1BBC; 1BJJ; 1BK9; 1BP2; 1BPQ; 1BUN; 1BVM; 1C1J; 1C74; 1CEH; 1CL5; 1CLP; 1DB4; 1DB5; 1DCY; 1DPY; 1FB2; 1FDK; 1FE5; 1FV0; 1FX9; 1FXF; 1G2X; 1G4I; 1GH4; 1GMZ; 1GOD; 1GP7; 1HN4; 1IJL; 1IRB; 1J1A; 1JIA; 1JLT; 1JQ8; 1JQ9; 1KPM; 1KQU; 1KVO; 1KVX; 1KVY; 1L8S; 1LE6; 1LE7; 1LN8; 1LX1; 1M8R; 1M8S; 1M8T; 1MC2; 1MF4; 1MG6; 1MH2; 1MH7; 1MH8; 1MKS; 1MKT; 1MKU; 1MKV; 1N29; 1O2E; 1O3W; 1OO1; 1OQS; 1OWS; 1OXL; 1OXR; 1OYF; 1P2P; 1P7O; 1PA0; 1PC9; 1PIR; 1PIS; 1PO8; 1POA; 1POB; 1POC; 1POD; 1POE; 1PP2; 1PPA; 1PSH; 1PSJ; 1Q6V; 1Q7A; 1QLL; 1RGB; 1S6B; 1S8G; 1S8H; 1S8I; 1SFV; 1SFW; 1SKG; 1SQZ; 1SV3; 1SV9; 1SXK; 1SZ8; 1T37; 1TD7; 1TDV; 1TG1; 1TG4; 1TGM; 1TH6; 1TJ9; 1TJK; 1TK4; 1TP2; 1UNE; 1VAP; 1VIP; 1VKQ; 1VL9; 1XXS; 1XXW; 1Y38; 1Y4L; 1Y6O; 1Y6P; 1Y75; 1YSK; 1YXH; 1YXL; 1ZM6; 1ZR8; 1ZWP; 1ZYX; 2AOZ; 2ARM; 2AZY; 2AZZ; 2B00; 2B01; 2B03; 2B04; 2B17; 2B96; 2BAX; 2BCH; 2BD1; 2BP2; 2BPP; 2DO2; 2DPZ; 2FNX; 2G58; 2GHN; 2GNS; 2GNY; 2H8I; 2I0U; 2NOT; 2O1N; 2OK9; 2OLI; 2OQD; 2OSH; 2OTF; 2OTH; 2OUB; 2OYF; 2PB8; 2PH4; 2PHI; 2PMJ; 2PVT; 2PWS; 2PYC; 2Q1P; 2Q2J; 2QHD; 2QHE; 2QHW; 2QOG; 2QU9; 2QUE; 2QVD; 2RD4; 2WG7; 2WG8; 2WG9; 2WQ5; 2ZBH; 2ZP3; 2ZP5; 3BJW; 3BP2; 3CBI; 3CXI; 3CYL; 3DIH; 3ELO; 3FVI; 3FVJ; 3G8F; 3G8G; 3G8H; 3GCI; 3H1X; 3HSW; 3HZD; 3HZW; 3I03; 3I3I; 3IQ3; 3JQ5; 3JQL; 3L30; 3L69; 3P2P; 4BP2; 4P2P; 5P2P; |
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