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PROSITE entry PS00114


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00114
Entry name [info] PRPP_SYNTHASE
Accession [info] PS00114
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00105

Name and characterization of the entry

Description [info] Phosphoribosyl pyrophosphate synthase signature.
Pattern [info] 
D-[LIM]-H-[SANDT]-x-[QS]-[IMSTAVF]-[QMLPH]-[GA]-[FY]-F-x(2)-P-
[LIVMFCT]-D.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 172 in 172 different sequences
Number of true positive hits 172 in 172 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 32
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 84.31 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] magnesium(?) at position 1
Site [info] magnesium(?) at position 3
Site [info] magnesium(?) at position 15
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 172 sequences 

KPR1_CANAX  (P46585), KPR1_SCHPO  (P41831), KPR1_YEAST  (P32895),
» more

UniProtKB/Swiss-Prot
False negative sequences		 32 sequences 

KPRH_STRCO  (Q9EWS0), KPRS1_ARCFU (O29666), KPRS2_ARCFU (O28853),
» more

PDB
[Detailed view]		 34 PDB

1DKR; 1DKU; 1IBS; 2H06; 2H07; 2H08; 2HCR; 3DAH; 3EFH; 3S5J; 4F8E; 4LYG;
» more