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PROSITE entry PS00105


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00105
Entry name [info] AA_TRANSFER_CLASS_1
Accession [info] PS00105
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00098

Name and characterization of the entry

Description [info] Aminotransferases class-I pyridoxal-phosphate attachment site.
Pattern [info] 
[GS]-[LIVMFYTAC]-[GSTA]-K-x(2)-[GSALVN]-[LIVMFA]-x-[GNAR]-{V}-R-[LIVMA]-
[GA].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 190 in 190 different sequences
Number of true positive hits 170 in 170 different sequences
Number of 'unknown' hits 0
Number of false positive hits 20 in 20 different sequences
Number of false negative sequences 112
Number of 'partial' sequences 6
Precision (true positives / (true positives + false positives)) 89.47 %
Recall (true positives / (true positives + false negatives)) 60.28 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] pyridoxal_phosphate at position 4
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 170 sequences 

1A111_ARATH (Q9S9U6), 1A112_ARATH (Q8GYY0), 1A11_ARATH  (Q06429),
» more

UniProtKB/Swiss-Prot
False negative sequences		 112 sequences 

1A110_ARATH (Q9LQ10), 1A1L1_BOVIN (Q5E9H2), 1A1L1_HUMAN (Q96QU6),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 6 sequences 

AAT1_PSEMZ  (P85906), AAT2_PSEMZ  (P85951), AATC_RABIT  (P12343),
» more

UniProtKB/Swiss-Prot
False positive sequences		 20 sequences 

BAME1_ARATH (O49545), BAME2_ARATH (Q9M2Z1), CLP1_NEUCR  (Q7SAB7),
» more

PDB
[Detailed view]		 180 PDB

1AAM; 1AAT; 1AAW; 1AHE; 1AHF; 1AHG; 1AHX; 1AHY; 1AJR; 1AJS; 1AMA; 1AMQ;
» more