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PROSITE entry PS00095


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PURL: https://purl.expasy.org/prosite/signature/PS00095

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General information about the entry

Entry name [info] C5_MTASE_2
Accession [info] PS00095
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2003 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00089

Name and characterization of the entry

Description [info] C-5 cytosine-specific DNA methylases C-terminal signature.
Pattern [info]
[RKQGTF]-x(2)-G-N-[SA]-[LIVF]-x-[VIP]-x-[LVMT]-x(3)-[LIVM]-x(3)-[LIVM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 78 in 78 different sequences
Number of true positive hits 68 in 68 different sequences
Number of 'unknown' hits 0
Number of false positive hits 10 in 10 different sequences
Number of false negative sequences 25
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 87.18 %
Recall (true positives / (true positives + false negatives)) 73.12 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
68 sequences

CMT2_ORYSJ  (Q5KQL9), DCM_ECO57   (P0AEE0), DCM_ECOLI   (P0AED9), 
» more

UniProtKB/Swiss-Prot
False negative sequences
25 sequences

CMT1_ORYSJ  (A0A0P0VUY4), CMT3_ORYSJ  (C0SQ89), DNM3A_CHICK (Q4W5Z4), 
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

MTG1_HERAU  (P25267)

		
UniProtKB/Swiss-Prot
False positive sequences
10 sequences

ATPB_MYCGI  (A4T8K2), ATPB_MYCLE  (P45823), CDAA_BACSU  (Q45589), 
» more

PDB
[Detailed view]
62 PDB

10MH; 1DCT; 1FJX; 1G55; 1HMY; 1M0E; 1MHT; 1SKM; 1SVU; 2C7O; 2C7P; 2C7Q;
» more