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PROSITE entry PS00092


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00092
Entry name [info] N6_MTASE
Accession [info] PS00092
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00087

Name and characterization of the entry

Description [info] N-6 Adenine-specific DNA methylases signature.
Pattern [info] 
[LIVMAC]-[LIVFYWA]-{DYP}-[DN]-P-P-[FYW].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 975 in 972 different sequences
Number of true positive hits 279 in 276 different sequences
Number of 'unknown' hits 11 in 11 different sequences
Number of false positive hits 685 in 685 different sequences
Number of false negative sequences 10
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 28.94 %
Recall (true positives / (true positives + false negatives)) 96.54 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 2
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 276 sequences 

CCRM_BRUA1  (B2S9Y5), CCRM_BRUA2  (Q2YMK2), CCRM_BRUA4  (A6WWI2),
» more

UniProtKB/Swiss-Prot
False negative sequences		 10 sequences 

EFM5_DICDI  (Q86A24), MT1A_MORBO  (P34720), MTC1_RHOHA  (P42828),
» more

UniProtKB/Swiss-Prot
'Unknown' sequences		 11 sequences 

HEMK1_HUMAN (Q9Y5R4), HEMK1_MOUSE (Q921L7), MGAL_HUMAN  (Q2M2H8),
» more

UniProtKB/Swiss-Prot
False positive sequences		 685 sequences 

AATR1_SCHPO (O14192), ACTL9_BOVIN (Q2T9W4), ACTL9_HUMAN (Q8TC94),
» more

PDB
[Detailed view]		 95 PDB

1AQI; 1AQJ; 1EG2; 1G38; 1G60; 1NW5; 1NW6; 1NW7; 1NW8; 1Q0S; 1Q0T; 1YF3;
» more