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PROSITE entry PS00078


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PURL: https://purl.expasy.org/prosite/signature/PS00078

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General information about the entry

Entry name [info] COX2
Accession [info] PS00078
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1997 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00075

Name and characterization of the entry

Description [info] CO II and nitrous oxide reductase dinuclear copper centers signature.
Pattern [info] 
V-x-H-x(33,40)-C-x(3)-C-x(3)-H-x(2)-M.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 325 in 325 different sequences
Number of true positive hits 325 in 325 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 15
Number of 'partial' sequences 9
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 95.59 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] copper at position 3
Site [info] copper at position 5
Site [info] copper at position 7
Site [info] copper at position 9
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 325 sequences 

AOX2_AERPE  (Q9YDX7), COX1_ACACA  (Q37370), COX1_DICCI  (Q2LCQ6),
» more

UniProtKB/Swiss-Prot
False negative sequences		 15 sequences 

COX2_DAUCA  (P27168), COX2_LYCGY  (O47677), COX2_ORYSJ  (P04373),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 9 sequences 

COX2_AMICA  (P29655), COX2_ATRSP  (P29656), COX2_GEOSD  (P29657),
» more

PDB
[Detailed view]		 184 PDB

1AR1; 1EHK; 1M56; 1M57; 1OCC; 1OCO; 1OCR; 1OCZ; 1QLE; 1V54; 1V55; 1XME;
» more