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PROSITE entry PS00071


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00071
Entry name [info] GAPDH
Accession [info] PS00071
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00069
Associated ProRule [info] PRU10009

Name and characterization of the entry

Description [info] Glyceraldehyde 3-phosphate dehydrogenase active site.
Pattern [info] 
[ASV]-S-C-[NT]-T-{S}-x-[LIM].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 409 in 409 different sequences
Number of true positive hits 393 in 393 different sequences
Number of 'unknown' hits 0
Number of false positive hits 16 in 16 different sequences
Number of false negative sequences 25
Number of 'partial' sequences 9
Precision (true positives / (true positives + false positives)) 96.09 %
Recall (true positives / (true positives + false negatives)) 94.02 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Site [info] active_site at position 3
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 393 sequences 

E4PD_CITK8  (A8APE1), E4PD_CROS8  (A7MJQ2), E4PD_ECO24  (A7ZR35),
» more

UniProtKB/Swiss-Prot
False negative sequences		 25 sequences 

E4PD_AERHH  (A0KGD2), E4PD_AERS4  (A4SRF2), E4PD_ALIF1  (Q5E7R0),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 9 sequences 

G3P2_BACCE  (P83077), G3PB_POPEU  (P84544), G3PC2_HORVU (P08477),
» more

UniProtKB/Swiss-Prot
False positive sequences		 16 sequences 

BLAA_STRCI  (P33651), CARL1_MOUSE (Q6EDY6), DDB1_DROME  (Q9XYZ5),
» more

PDB
[Detailed view]		 142 PDB

1A7K; 1B7G; 1CER; 1CF2; 1CRW; 1DBV; 1DC3; 1DC4; 1DC5; 1DC6; 1DSS; 1GAD;
» more