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PROSITE entry PS00062


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PURL: https://purl.expasy.org/prosite/signature/PS00062

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General information about the entry

Entry name [info] ALDOKETO_REDUCTASE_2
Accession [info] PS00062
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00061

Name and characterization of the entry

Description [info] Aldo/keto reductase family signature 2.
Pattern [info] 
[LIVMFY]-x(8)-{L}-[KREQ]-{K}-[LIVM]-G-[LIVM]-[SC]-N-[FY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 173 in 173 different sequences
Number of true positive hits 170 in 170 different sequences
Number of 'unknown' hits 0
Number of false positive hits 3 in 3 different sequences
Number of false negative sequences 37
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 98.27 %
Recall (true positives / (true positives + false negatives)) 82.13 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 170 sequences 

6DCS_SOYBN  (P26690), A1A1A_DANRE (Q6AZW2), A1A1B_DANRE (Q568L5),
» more

UniProtKB/Swiss-Prot
False negative sequences		 37 sequences 

AKR1_ORYSI  (B8ASB2), AKR1_ORYSJ  (Q0JE32), AKR1_SOYBN  (C6TBN2),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 2 sequences 

CROB_LEPLU  (P49261), DHGP_ASPNG  (P55804)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			3 sequences
			


			
CO6A1_XENLA (Q801S8), CUE3_YEAST  (P53137), SFH2_ARATH  (F4JVA9)


				
	

	

		PDB
[Detailed view]		
		
			366 PDB
			


			1ABN; 1ADS; 1AE4; 1AFS; 1AH0; 1AH3; 1AH4; 1AZ1; 1AZ2; 1C9W; 1CWN; 1DLA; 
			
			

			» more