PROSITE entry PS00062

View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission

General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00062
Entry name [info]	ALDOKETO_REDUCTASE_2
Accession [info]	PS00062
Entry type [info]	PATTERN
Date [info]	01-APR-1990 CREATED; 01-DEC-2004 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00061

Name and characterization of the entry

Description [info]	Aldo/keto reductase family signature 2.
Pattern [info]	[LIVMFY]-x(8)-{L}-[KREQ]-{K}-[LIVM]-G-[LIVM]-[SC]-N-[FY].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	170 in 170 different sequences
Number of true positive hits	167 in 167 different sequences
Number of 'unknown' hits	0
Number of false positive hits	3 in 3 different sequences
Number of false negative sequences	37
Number of 'partial' sequences	2

Precision (true positives / (true positives + false positives))	98.24 %
Recall (true positives / (true positives + false negatives))	81.86 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	1
Version [info]	1

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	167 sequences 6DCS_SOYBN (P26690), A1A1A_DANRE (Q6AZW2), A1A1B_DANRE (Q568L5), » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	37 sequences AKCL1_HUMAN (Q5T2L2), AKR1_ORYSI (B8ASB2), AKR1_ORYSJ (Q0JE32), » more
UniProtKB/Swiss-Prot 'Partial' sequences	2 sequences CROB_LEPLU (P49261), DHGP_ASPNG (P55804)
UniProtKB/Swiss-Prot False positive sequences	3 sequences CO6A1_XENLA (Q801S8), CUE3_YEAST (P53137), SFH2_ARATH (F4JVA9)
PDB [Detailed view]	366 PDB 1ABN; 1ADS; 1AE4; 1AFS; 1AH0; 1AH3; 1AH4; 1AZ1; 1AZ2; 1C9W; 1CWN; 1DLA; » more