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PROSITE entry PS00060


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PURL: https://purl.expasy.org/prosite/signature/PS00060

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General information about the entry

Entry name [info] ADH_IRON_2
Accession [info] PS00060
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00059

Name and characterization of the entry

Description [info] Iron-containing alcohol dehydrogenases signature 2.
Pattern [info]
[GSW]-x-[LIVTSACD]-[GH]-x(2)-[GSAE]-[GSHYQ]-x-[LIVTP]-[GAST]-[GAS]-x(3)-
[LIVMT]-x-[HNS]-[GA]-x-[GTAC].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 38 in 38 different sequences
Number of true positive hits 35 in 35 different sequences
Number of 'unknown' hits 0
Number of false positive hits 3 in 3 different sequences
Number of false negative sequences 36
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 92.11 %
Recall (true positives / (true positives + false negatives)) 49.30 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
35 sequences

4HBDH_CLOK5 (P38945), ADH1_CLOSA  (P13604), ADH2_ECOLI  (P37686), 
» more

UniProtKB/Swiss-Prot
False negative sequences
36 sequences

4HBDH_CUPNE (Q59104), ADH1_GEOTN  (A4IP64), ADHA_THEET  (Q9F282), 
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

MACA2_RHOOP (P56870)

		
UniProtKB/Swiss-Prot
False positive sequences
3 sequences

CAP2_HUMAN  (P40123), CAP2_PONAB  (Q5R5X8), GIF1_ORYSJ  (Q6AVI1)

		
PDB
[Detailed view]
33 PDB

1JPU; 1JQ5; 1JQA; 1KQ3; 1OJ7; 1RRM; 2BI4; 2BL4; 3BFJ; 3OWO; 3OX4; 4QGS;
» more