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PROSITE entry PS00058


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PURL: https://purl.expasy.org/prosite/signature/PS00058

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General information about the entry

Entry name [info] DNA_MISMATCH_REPAIR_1
Accession [info] PS00058
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-DEC-2004 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00057

Name and characterization of the entry

Description [info] DNA mismatch repair proteins mutL / hexB / PMS1 signature.
Pattern [info] 
G-F-R-G-E-[AG]-L.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 461 in 461 different sequences
Number of true positive hits 458 in 458 different sequences
Number of 'unknown' hits 0
Number of false positive hits 3 in 3 different sequences
Number of false negative sequences 10
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 99.35 %
Recall (true positives / (true positives + false negatives)) 97.86 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 458 sequences 

HEXB_STRPN  (P0A3R1), HEXB_STRR6  (P0A3R2), MLH1_ARATH  (Q9ZRV4),
» more

UniProtKB/Swiss-Prot
False negative sequences		 10 sequences 

MUTL_ANAD2  (B8J9F5), MUTL_ANADE  (Q2IIL0), MUTL_ANASK  (B4UCW3),
» more

UniProtKB/Swiss-Prot
False positive sequences		 3 sequences 

S2542_HUMAN (Q86VD7), S2542_MOUSE (Q8R0Y8), S2542_RAT   (P0C546)


				
	

	

		PDB
[Detailed view]		
		
			25 PDB
			


			1B62; 1B63; 1BKN; 1EA6; 1H7S; 1H7U; 1NHH; 1NHI; 1NHJ; 3H4L; 4P7A; 5AKB; 
			
			

			» more