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PROSITE entry PS00046


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PURL: https://purl.expasy.org/prosite/signature/PS00046

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General information about the entry

Entry name [info] HISTONE_H2A
Accession [info] PS00046
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-NOV-1995 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00045

Name and characterization of the entry

Description [info] Histone H2A signature.
Pattern [info] 
[AC]-G-L-x-F-P-V.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 233 in 233 different sequences
Number of true positive hits 227 in 227 different sequences
Number of 'unknown' hits 0
Number of false positive hits 6 in 6 different sequences
Number of false negative sequences 18
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 97.42 %
Recall (true positives / (true positives + false negatives)) 92.65 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 227 sequences 

H2A1A_HUMAN (Q96QV6), H2A1B_HUMAN (P04908), H2A1B_MOUSE (C0HKE1),
» more

UniProtKB/Swiss-Prot
False negative sequences		 18 sequences 

H2A4_ARATH  (Q9LZ46), H2A8_ORYSI  (A2ZK26), H2AB1_HUMAN (P0C5Y9),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 1 sequence 

H2A_OLILU   (P82897)


				
	

	

		UniProtKB/Swiss-Prot
False positive sequences		
		
			6 sequences
			


			
CBH_CLOPE   (P54965), COXX_HYPNA  (Q0C3D1), MCD4_ASPFU  (Q4W9R7), 

			
			» more
			


				
	

	

		PDB
[Detailed view]		
		
			772 PDB
			


			1AOI; 1EQZ; 1F66; 1HIO; 1HQ3; 1ID3; 1KX3; 1KX4; 1KX5; 1M18; 1M19; 1M1A; 
			
			

			» more