PROSITE entry PS00041

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS00041
Entry name [info]	HTH_ARAC_FAMILY_1
Accession [info]	PS00041
Entry type [info]	PATTERN
Date [info]	01-APR-1990 CREATED; 01-APR-2006 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00040

Name and characterization of the entry

Description [info]

Bacterial regulatory proteins, araC family signature.

Pattern [info]

[KRQ]-[LIVMA]-x(2)-[GSTALIV]-{FYWPGDN}-x(2)-[LIVMSA]-x(4,9)-[LIVMF]-x-
{PLH}-[LIVMSTA]-[GSTACIL]-{GPK}-{F}-x-[GANQRF]-[LIVMFY]-x(4,5)-[LFY]-
x(3)-[FYIVA]-{FYWHCM}-{PGVI}-x(2)-[GSADENQKR]-x-[NSTAPKL]-[PARL].

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	330 in 328 different sequences
Number of true positive hits	221 in 219 different sequences
Number of 'unknown' hits	1
Number of false positive hits	108 in 108 different sequences
Number of false negative sequences	47
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	67.17 %
Recall (true positives / (true positives + false negatives))	82.46 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	2
Version [info]	2

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	219 sequences AARP_PROST (P43463), ADAA_BACSU (P19219), ADA_ECOLI (P06134), » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	47 sequences FEAR_ECOLI (Q47129), HPTR_STAA3 (Q2FK47), HPTR_STAA8 (Q2G1E1), » more
UniProtKB/Swiss-Prot 'Unknown' sequences	1 sequence MRP7_CAEEL (Q9U2G5)
UniProtKB/Swiss-Prot False positive sequences	108 sequences AAM_RHOER (K9NBS6), ABGR_ECOLI (P77744), AIPS_SACS2 (Q7LXU6), » more
PDB [Detailed view]	22 PDB 1BL0; 1D5Y; 1U8B; 1WPK; 1XS9; 1ZGW; 2K9S; 3GBG; 3MKL; 4FE4; 4FE7; 5SUW; » more