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PROSITE entry PS00031


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00031
Entry name [info] NUCLEAR_REC_DBD_1
Accession [info] PS00031
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00031

Name and characterization of the entry

Description [info] Nuclear hormones receptors DNA-binding region signature.
Pattern [info] 
C-x(2)-C-x(1,2)-[DENAVSPHKQT]-x(5,6)-[HNY]-[FY]-x(4)-C-x(2)-C-x(2)-F(2)-
x-R.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 462 in 462 different sequences
Number of true positive hits 462 in 462 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 11
Number of 'partial' sequences 9
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.67 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Site [info] zinc at position 1
Site [info] zinc at position 3
Site [info] zinc at position 10
Site [info] zinc at position 12
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 462 sequences 

7UP1_DROME  (P16375), 7UP2_DROME  (P16376), ANDR_AQUCT  (Q7T1K4),
» more

UniProtKB/Swiss-Prot
False negative sequences		 11 sequences 

NH108_CAEEL (O45449), NH130_CAEEL (O16963), NH167_CAEEL (O17683),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 9 sequences 

ESR1_ANOCA  (Q9YHT3), ESR1_ASPUN  (Q91424), ESR1_MACMU  (P49886),
» more

PDB
[Detailed view]		 112 PDB

1A6Y; 1BY4; 1CIT; 1DSZ; 1GA5; 1GDC; 1GLU; 1HCP; 1HCQ; 1HLZ; 1HRA; 1KB2;
» more