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PROSITE entry PS00022


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS00022
Entry name [info] EGF_1
Accession [info] PS00022
Entry type [info] PATTERN
Date [info] 01-APR-1990 CREATED;
01-APR-2006 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00021

Name and characterization of the entry

Description [info] EGF-like domain signature 1.
Pattern [info] 
C-x-C-x(2)-{V}-x(2)-G-{C}-x-C.

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 3'541 in 1'023 different sequences
Number of true positive hits 3'225 in 787 different sequences
Number of 'unknown' hits 128 in 50 different sequences
Number of false positive hits 188 in 186 different sequences
Number of false negative sequences 367
Number of 'partial' sequences 4
Precision (true positives / (true positives + false positives)) 94.49 %
Recall (true positives / (true positives + false negatives)) 89.78 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 41
Site [info] disulfide at position 1
Site [info] disulfide at position 3
Site [info] disulfide at position 10
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences		 787 sequences 

ABCG1_ARTBC (D4AYW0), ABCGO_DICDI (Q54T02), ADA11_HUMAN (O75078),
» more

UniProtKB/Swiss-Prot
False negative sequences		 367 sequences 

AD26A_MOUSE (Q9R158), ADA12_HUMAN (O43184), ADA12_MOUSE (Q61824),
» more

UniProtKB/Swiss-Prot
'Partial' sequences		 4 sequences 

FAXD_NOTSN  (P0CY52), HYAL_CONAQ  (I0CME8), NID1_RAT(P08460),
» more

UniProtKB/Swiss-Prot
'Unknown' sequences		 50 sequences 

ITB1A_XENLA (P12606), ITB1B_XENLA (P12607), ITB1_BOVIN  (P53712),
» more

UniProtKB/Swiss-Prot
False positive sequences		 186 sequences 

ABCA2_HUMAN (Q9BZC7), ABCA2_MOUSE (P41234), ABCA2_RAT   (Q9ESR9),
» more

PDB
[Detailed view]		 495 PDB

1A3P; 1APO; 1AUT; 1BF9; 1C5M; 1CCF; 1DAN; 1DVA; 1EDM; 1EGF; 1EPG; 1EPH;
» more